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Note 5 - Stockholders' Equity and Common Stock Warrants (Tables)
6 Months Ended
Jun. 30, 2021
Notes Tables  
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
   

Outstanding

   

Range of exercise

price per share

   

Expiration dates

Common stock warrants issued in 2017 related to Series A convertible preferred stock offering

    903,870         $33.30      

March 2022

Common stock warrants issued in 2018 related to the January 2018 Offering

    1,181,421    

 

$12.00 - $15.00    

January 2023

Common stock warrants issued related to the May 2019 Offering

    1,382,913    

 

$5.00 - $6.11875    

May and December 2024

Common stock warrants issued related to the November 2019 Offering

    213,570         $0.35      

November 2024

Common stock warrants issued related to the December 2019 Offering

    313,339    

 

$0.4335 - $0.6981    

December 2024 and June 2025

Common stock warrants issued related to the May 2020 Offering

    571,429        

$1.31

     

March 2025

Common stock warrants issued related to May 2020 Investor Warrant Exercise

    250,000         $0.5938      

November 2025

Common stock warrants issued related to the February 2021 Offering

    1,682,927         $1.28      

February 2026

      6,499,469