Note 9 - Income Taxes - Deferred Tax Assets and Liabilities (Details) - USD ($)	Dec. 31, 2020	Dec. 31, 2019
Net operating loss carryforwards	$ 3,864,189	$ 1,504,496
Stock-based compensation	1,571,227	1,381,750
Orphan Drug credits	541,384	81,700
Lease liability	38,394	63,589
Capitalized start-up costs and other	10,709,631	9,187,898
Valuation allowance	(14,906,646)	(12,051,440)
Deferred tax assets	1,818,179	167,993
Intangible assets	(2,223,678)	(2,223,678)
Right of use asset	(38,394)	(63,589)
Deferred tax liabilities	(2,262,072)	(2,287,267)
Net deferred tax liability	$ (443,893)	$ (2,119,274)