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Note 5 - Stockholders' Equity and Common Stock Warrants (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
May 31, 2020
Dec. 31, 2019
Nov. 30, 2019
May 31, 2019
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Deemed Dividend From Warrant Exchange         $ 1,950,378
Class of Warrant or Rights, Expired (in shares)             0  
Class of Warrant or Right, Exercised During Period (in shares)             19,106,504  
Proceeds from Warrant Exercises             $ 8,046,103
The May 2020 Offering Warrants [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) 571,429              
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) $ 1.3125       $ 1.3125   $ 1.3125  
Warrants and Rights Outstanding, Term (Year) 5 years              
Prior Warrant [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) 5,000,000              
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) $ 0.35              
Class of Warrant or Right, Exchange, Additional Consideration Per Share (in dollars per share) $ 0.125              
New Warrants Issued May 8, 2020 [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) 5,000,000              
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) $ 0.5263              
The May 2020 PA Warrants [Member] | H.C Wainwright & Co., LLC [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) 250,000              
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) $ 0.5938              
Warrants Issued in Connection with the December 2019 Offering [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)   6,266,787            
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)   $ 0.4335     $ 0.6981   $ 0.6981  
Placement Agent Warrant [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)   313,339 571,429 65,853        
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)   $ 0.6981 $ 0.4375 $ 6.11875        
Warrants and Rights Outstanding, Term (Year)   5 years 5 years 5 years        
Warrants Issued in Connection with the November 2019 Offering [Member]                
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)     $ 0.35          
Class of Warrant or Right, Issued During Period (in shares)     6,324,143          
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right (in shares)     1          
Warrants with 18 Months Term Issued in Connection with the November 2019 Offering [Member]                
Warrants and Rights Outstanding, Term (Year)     1 year 180 days          
Class of Warrant or Right, Issued During Period (in shares)     11,428,572          
Warrants with 5 Years Term Issued in Connection with the November 2019 Offering [Member]                
Warrants and Rights Outstanding, Term (Year)     5 years          
Class of Warrant or Right, Issued During Period (in shares)     11,428,572          
The May 2020 Offering [Member]                
Stock Issued During Period, Shares, New Issues (in shares) 11,428,572              
Shares Issued, Price Per Share (in dollars per share) $ 1.05              
Proceeds from Issuance of Common Stock $ 10,300,000              
December 2019 Public Offering [Member]                
Stock Issued During Period, Shares, New Issues (in shares)   6,266,787            
Shares Issued, Price Per Share (in dollars per share)   $ 0.5585            
Proceeds from Issuance or Sale of Equity, Total   $ 3,000,000            
November 2019 Public Offering [Member]                
Stock Issued During Period, Shares, New Issues (in shares)     5,104,429          
Shares Issued, Price Per Share (in dollars per share)     $ 0.35          
Proceeds from Issuance or Sale of Equity, Total     $ 3,300,000          
Stock and Warrants Issued During Period, Number of Securities Called by Stock and Warrants (in shares)     22,857,144          
May 2019 Public Offering [Member]                
Stock Issued During Period, Shares, New Issues (in shares)       1,317,060        
Shares Issued, Price Per Share (in dollars per share)       $ 4.895        
Proceeds from Issuance or Sale of Equity, Total       $ 5,600,000        
Warrants Issued in Connection with May 2019 Public Offering [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)       1,317,060        
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)       $ 5