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Note 5 - Stockholders' Equity and Common Stock Warrants (Tables)
6 Months Ended
Jun. 30, 2020
Notes Tables  
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
   
Outstanding
 
Range of exercise
price per shar
 
Expiration dates
Common stock warrants issued in 2017 related to Series A convertible preferred stock offering
   
903,870
   
 
$33.30
 
 
March 2022
Common stock warrants issued in 2018 related to the common stock offering    
1,181,375
   
$12.00
-
$15.00
 
January 2023
Common stock warrants issued related to the May 2019 offering    
1,382,913
   
$5.00
-
$6.11875
 
November 2024
Common stock warrants issued related to the November 2019 offering    
514,283
   
$0.35
-
$0.4375
 
May 2024
Common stock warrants issued related to the December 2019 offering
   
313,339
   
 
$0.6981
 
 
December 2024
Common stock warrants issued related to the May 2020 offering
   
571,429
   
 
$1.3125
 
 
May 2025
Common stock warrants issued related to May 2020 investor warrant exercise    
4,250,000
   
$0.5263
-
$0.5938
 
November 2025
     
9,117,209