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Note 3 - Basis of Presentation and Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2019
Notes Tables  
Fair Value Measurements, Recurring and Nonrecurring [Table Text Block]
   
Fair value measurement at
reporting date using
 
(in thousands)
 
Quoted prices
in active
markets for
identical
assets
(Level 1)
   
Significant
other
observable
inputs
(Level 2)
   
Significant
unobservable
inputs
(Level 3)
 
December 31, 2019:
 
 
 
 
 
 
 
 
 
 
 
 
Assets:
                       
Cash equivalents
  $
14,006,193
    $
    $
 
December 31, 2018:
 
 
 
 
 
 
 
 
 
 
 
 
Assets:
                       
Cash equivalents
  $
7,990,900
    $
    $
 
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   
December 31,
 
   
2019
   
2018
 
Common stock warrants
   
22,385,141
     
2,087,012
 
Stock options
   
309,276
     
203,736
 
     
22,694,417
     
2,290,748