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Note 2 - Liquidity (Details Textual) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended
Jan. 22, 2018
Jan. 31, 2018
Dec. 31, 2018
Dec. 31, 2017
Common Stock, Par or Stated Value Per Share $ 0.001   $ 0.001 $ 0.001
Conversion From Series A Preferred Stock to Common Stock [Member]        
Conversion of Stock, Shares Issued 1,400,462 1,400,462    
Warrants Issued in Connection with the January 2018 Offering [Member]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights 1,000,000 1,000,000    
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 12 $ 12    
Class of Warrant or Right, Term 5 years      
Warrants Issued in Connection with the January 2018 Offering [Member] | Maximum [Member]        
Class of Warrant or Right, Exercise Price of Warrants or Rights     $ 15  
Additional Warrants [Member]        
Class of Warrant or Right, Exercise Price of Warrants or Rights   12    
Underwriter Warrants [Member]        
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 15 $ 15    
Class of Warrant or Right, Term 5 years 5 years    
Underwriter Warrants [Member] | Maximum [Member]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights 50,000 50,000    
January 2018 Offering [Member]        
Stock Issued During Period, Shares, New Issues 1,000,000 1,000,000    
Share Price $ 12      
Proceeds from Issuance or Sale of Equity, Total $ 10,800 $ 10,800    
January 2018 Offering [Member] | Additional Warrants [Member]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights 131,375