Note 4 - Acquisition - Pro Forma Financial Information (Details)	12 Months Ended
Dec. 31, 2016 USD ($) $ / shares
Net revenues
Diffusion LLC [Member]
Net loss	$ (16,471,398)
Basic and diluted loss per share (in dollars per share) \| $ / shares	$ (1.60)

The pro forma basic and diluted net income per share for a period as if the business combination or combinations had been completed at the beginning of a period.

No definition available.

+ Details

Name:	dffn_BusinessAcquisitionProFormaEarningsPerShareBasicAndDiluted
Namespace Prefix:	dffn_
Data Type:	num:perShareItemType
Balance Type:	na
Period Type:	duration

- Definition

The pro forma net Income or Loss for the period as if the business combination or combinations had been completed at the beginning of a period.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 805
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(2)-(3)
-URI http://asc.fasb.org/extlink&oid=79982066&loc=d3e1392-128463

+ Details

Name:	us-gaap_BusinessAcquisitionsProFormaNetIncomeLoss
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

The pro forma revenue for a period as if the business combination or combinations had been completed at the beginning of the period.

+ References

+ Details

Name:	us-gaap_BusinessAcquisitionsProFormaRevenue
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Details

Name:	us-gaap_BusinessAcquisitionAxis=dffn_DiffusionLLCMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type: