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Note 14 - Fair Value Measurements (Tables)
12 Months Ended
Dec. 31, 2017
Notes Tables  
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
   
December 31, 2017
 
   
(Level 1)
   
(Level 2)
   
(Level 3)
 
Assets
 
 
 
 
 
 
 
 
 
 
 
 
Cash and cash equivalents
  $
8,896,468
    $
    $
 
Liabilities
 
 
 
 
 
 
 
 
 
 
 
 
Common stock warrant liability
  $
    $
    $
 
   
December 31, 2016
 
   
(Level 1)
   
(Level 2)
   
(Level 3)
 
Assets
 
 
 
 
 
 
 
 
 
 
 
 
Cash and cash equivalents
  $
1,552,852
    $
    $
 
Liabilities
 
 
 
 
 
 
 
 
 
 
 
 
Common stock warrant liability
  $
    $
    $
 
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
   
Common Stock
Warrant Liability
 
Balance at December 31, 2016
  $
 
Issued in connection with the Series A convertible preferred stock
   
35,225,846
 
Change in fair value
   
(22,072,322
)
Reclassification of Series A warrants to additional paid in capital
   
(13,153,524
)
Balance at December 31, 2017
  $
 
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
Stock price
  $
1.44
 
Exercise price
  $
2.22
 
Expected term (in years)
   
4.38
 
Risk-free interest rate
   
1.9
%
Expected volatility
   
104.1
%
Dividend yield