Note 4 - Acquisition - Purchase Price Consideration (Details) - RestorGenex [Member] - Diffusion LLC [Member]	Jan. 08, 2016 USD ($)
Fair value of RestorGenex shares outstanding	$ 19,546,000
Estimated fair value of RestorGenex stock options outstanding	1,321,000
Estimated fair value of RestorGenex warrants outstanding	384,000
CVRs – RES-440 product candidate	10,000
Total purchase price	$ 21,261,000

- Definition

Amount of preliminary purchase consideration consisting of the fair value of assets transferable by the acquirer, liabilities obtainable by the acquirer, and equity interest issuable by the acquirer.

+ References

No definition available.

+ Details

Name:	dffn_BusinessCombinationPreliminaryPurchasePriceConsideration
Namespace Prefix:	dffn_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

Amount of contingent value rights in the preliminary purchase price consideration.

+ References

No definition available.

+ Details

Name:	dffn_BusinessCombinationPreliminaryPurchasePriceConsiderationContingentValueRights
Namespace Prefix:	dffn_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

Estimated fair value of stock options assumed in the preliminary purchase price consideration.

+ References

No definition available.

+ Details

Name:	dffn_BusinessCombinationPreliminaryPurchasePriceConsiderationEstimatedFairValueOfStockOptionsAssumed
Namespace Prefix:	dffn_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

Estimated fair value of warrants assumed in the preliminary purchase price consideration.

+ References

No definition available.

+ Details

Name:	dffn_BusinessCombinationPreliminaryPurchasePriceConsiderationEstimatedFairValueOfWarrantsAssumed
Namespace Prefix:	dffn_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

Fair value of shares outstanding in the preliminary purchase price consideration.

+ References

No definition available.

+ Details

Name:	dffn_BusinessCombinationPreliminaryPurchasePriceConsiderationFairValueOfSharesOutstanding
Namespace Prefix:	dffn_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Details

Name:	us-gaap_BusinessAcquisitionAxis=dffn_RestorGenexMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	dei_LegalEntityAxis=dffn_DiffusionLLCMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type: