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Note 3 - Basis of Presentation and Summary of Significant Accounting Policies (Details Textual) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2017
Jan. 01, 2017
Dec. 31, 2016
Sep. 30, 2016
Jan. 08, 2016
Previously Capitalized Offering Costs Expensed During the Period $ 98,000          
Goodwill 6,929,258 $ 6,929,258   $ 6,929,258    
Indefinite-Lived Intangible Assets (Excluding Goodwill) 8,639,000 8,639,000   8,639,000    
Impairment of Long-Lived Assets to be Disposed of 0 0        
Accounting Standards Update 2016-09 [Member]            
Cumulative Effect of New Accounting Principle in Period of Adoption     $ 1,000      
Diffusion LLC [Member]            
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Intangible Assets, Other than Goodwill           $ 9,600,000
Goodwill           6,929,258
RES-529 [Member] | Diffusion LLC [Member]            
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Intangible Assets, Other than Goodwill           8,600,000
RES-440 [Member]            
Indefinite-Lived Intangible Assets (Excluding Goodwill)         $ 0  
RES-440 [Member] | Diffusion LLC [Member]            
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Intangible Assets, Other than Goodwill           $ 1,000,000
Fair Value, Inputs, Level 3 [Member] | Convertible Note, Series B [Member]            
Convertible Debt, Fair Value Disclosures $ 500,000 $ 500,000   600,000    
Fair Value, Inputs, Level 3 [Member] | The 2016 Convertible Notes [Member]            
Convertible Debt, Fair Value Disclosures       $ 2,000,000