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Note 6 - Other Accrued Expenses and Liabilities (Tables)
9 Months Ended
Sep. 30, 2017
Notes Tables  
Other Current Liabilities [Table Text Block]
   
September 30,
2017
   
December
31,
2016
 
Accrued interest payable
  $
36,029
    $
29,359
 
Accrued Series A dividends
   
725,774
     
 
Accrued payroll and payroll related expenses
   
398,859
     
399,740
 
Accrued professional fees
   
114,268
     
72,855
 
Accrued clinical studies expenses
   
88,175
     
220,978
 
Other accrued expenses
   
52,602
     
151,332
 
Total
  $
1,415,707
    $
874,264