Note 5 - Accrued Expenses and Liabilities - Summary of Accrued Expenses (Details) - USD ($)	Jun. 30, 2017	Dec. 31, 2016
Accrued interest payable	$ 119,975	$ 29,359
Accrued Series A dividends	475,414
Accrued payroll and payroll related expenses	251,465	399,740
Accrued professional fees	340,481	72,855
Accrued clinical studies expenses	27,071	220,978
Other accrued expenses	18,290	151,332
Total	$ 1,232,696	$ 874,264