Summary of Significant Accounting Policies - Additional Information (Detail) |
3 Months Ended | 6 Months Ended | 12 Months Ended | ||
---|---|---|---|---|---|
Dec. 31, 2016
USD ($)
|
Dec. 31, 2016
USD ($)
|
Dec. 31, 2016
USD ($)
Segment
|
Dec. 31, 2015
USD ($)
|
Dec. 31, 2014
USD ($)
|
|
Significant Accounting Policies [Line Items] | |||||
Goodwill impairment | $ 0 | ||||
Impairment charge | $ 0 | $ 599,118,000 | $ 198,700,000 | $ 0 | |
Number of operating business segment | Segment | 1 | ||||
Aldurazyme | Minimum | |||||
Significant Accounting Policies [Line Items] | |||||
Payment received as percentage of net product sales | 39.50% | 39.50% | 39.50% | ||
Aldurazyme | Maximum | |||||
Significant Accounting Policies [Line Items] | |||||
Payment received as percentage of net product sales | 50.00% | 50.00% | 50.00% |