Segment Information by Product Revenue (Detail) - USD ($) $ in Thousands |
12 Months Ended | ||
---|---|---|---|
Dec. 31, 2015 |
Dec. 31, 2014 |
Dec. 31, 2013 |
|
Revenue from External Customer [Line Items] | |||
Net product revenues | $ 884,522 | $ 738,416 | $ 538,360 |
Vimizim | |||
Revenue from External Customer [Line Items] | |||
Net product revenues | 228,147 | 77,319 | 85 |
Naglazyme | |||
Revenue from External Customer [Line Items] | |||
Net product revenues | 303,090 | 334,447 | 271,244 |
Kuvan | |||
Revenue from External Customer [Line Items] | |||
Net product revenues | 239,336 | 202,987 | 167,422 |
Aldurazyme | |||
Revenue from External Customer [Line Items] | |||
Net product revenues | 97,912 | 105,616 | 83,545 |
Firdapse | |||
Revenue from External Customer [Line Items] | |||
Net product revenues | $ 16,037 | $ 18,047 | $ 16,064 |