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Property Plant and Equipment (Detail) (USD $)
In Thousands, unless otherwise specified
Dec. 31, 2014
Dec. 31, 2013
Property, Plant and Equipment [Line Items]    
Property, plant and equipment, gross $ 752,405us-gaap_PropertyPlantAndEquipmentGross $ 504,359us-gaap_PropertyPlantAndEquipmentGross
Less: Accumulated depreciation (228,889)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment (185,043)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
Total property, plant and equipment, net 523,516us-gaap_PropertyPlantAndEquipmentNet 319,316us-gaap_PropertyPlantAndEquipmentNet
Leasehold Improvements    
Property, Plant and Equipment [Line Items]    
Property, plant and equipment, gross 39,297us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LeaseholdImprovementsMember
73,420us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LeaseholdImprovementsMember
Building and Improvements    
Property, Plant and Equipment [Line Items]    
Property, plant and equipment, gross 335,991us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_BuildingAndBuildingImprovementsMember
159,678us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_BuildingAndBuildingImprovementsMember
Manufacturing and Laboratory Equipment    
Property, Plant and Equipment [Line Items]    
Property, plant and equipment, gross 124,564us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_TechnologyEquipmentMember
95,126us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_TechnologyEquipmentMember
Computer Hardware and Software    
Property, Plant and Equipment [Line Items]    
Property, plant and equipment, gross 97,032us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_ComputerEquipmentMember
74,948us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_ComputerEquipmentMember
Furniture and Equipment    
Property, Plant and Equipment [Line Items]    
Property, plant and equipment, gross 13,717us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_FurnitureAndFixturesMember
12,367us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_FurnitureAndFixturesMember
Land Improvements    
Property, Plant and Equipment [Line Items]    
Property, plant and equipment, gross 4,106us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LandImprovementsMember
 
Land    
Property, Plant and Equipment [Line Items]    
Property, plant and equipment, gross 29,358us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LandMember
11,608us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LandMember
Construction-in-Progress    
Property, Plant and Equipment [Line Items]    
Property, plant and equipment, gross $ 108,340us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_ConstructionInProgressMember
$ 77,212us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_ConstructionInProgressMember