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Property Plant and Equipment (Detail) (USD $)
In Thousands, unless otherwise specified
Sep. 30, 2013
Dec. 31, 2012
Property, Plant and Equipment [Line Items]    
Leasehold improvements $ 67,083 $ 65,918
Building and improvements 154,479 144,700
Manufacturing and laboratory equipment 88,865 79,915
Computer hardware and software 63,164 56,011
Furniture and equipment 12,152 11,143
Land 11,608 11,608
Construction-in-progress 64,756 64,300
Property, Plant and Equipment, Gross, Total 462,107 433,595
Less: Accumulated depreciation (176,443) (149,122)
Total property, plant and equipment, net $ 285,664 $ 284,473 [1]
[1] December 31, 2012 balances were derived from the audited Consolidated Financial Statements included in the Company's Annual Report on Form 10-K for the year ended December 31, 2012, filed with the Securities and Exchange Commission (the SEC) on February 26, 2013.