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Share-based payments (Summary of Stock Option Activity) (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Stock Options [Member]    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Outstanding beginning balance, Common shares under option 2,208,057  
Granted, Common shares under option 629,877  
Exercised, Common shares under option (25,942)  
Forfeited, Common shares under option (6,255)  
Outstanding ending balance, Common shares under option 2,805,737 2,208,057
Exercisable, Common shares under option 1,338,173  
Outstanding beginning balance, Weighted average exercise price (per share) $ 42.55  
Granted, Weighted average exercise price (per share) 57.70  
Exercised, Weighted average exercise price (per share) 38.01  
Forfeited, Weighted average exercise price (per share) 43.02  
Outstanding ending balance, Weighted average exercise price (per share) 45.99 $ 42.55
Exercisable, Weighted average exercise price (per share) $ 37.19  
Outstanding, Weighted average remaining contractual life (in years) 8 years 7 years 8 months 12 days
Exercisable, Weighted average remaining contractual life (in years) 6 years 8 months 12 days  
Outstanding beginning balance, Aggregate intrinsic value $ 41,884  
Exercised, Aggregate intrinsic value 573  
Outstanding ending balance, Aggregate intrinsic value 37,437 $ 41,884
Exercisable, Aggregate intrinsic value $ 29,251  
Premium Priced Stock Options [Member]    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Outstanding beginning balance, Common shares under option 1,017,064  
Forfeited, Common shares under option (9,576)  
Outstanding ending balance, Common shares under option 1,007,488 1,017,064
Exercisable, Common shares under option 1,192  
Outstanding beginning balance, Weighted average exercise price (per share) $ 91.24  
Forfeited, Weighted average exercise price (per share) 90.93  
Outstanding ending balance, Weighted average exercise price (per share) 91.24 $ 91.24
Exercisable, Weighted average exercise price (per share) $ 90.93  
Outstanding, Weighted average remaining contractual life (in years) 5 years 4 months 24 days 5 years 8 months 12 days
Exercisable, Weighted average remaining contractual life (in years) 5 years 7 months 6 days