Exhibit 3.425

CERTIFICATE OF FORMATION

OF

TWO RIVERS PHYSICIAN PRACTICES, LLC

Pursuant to Section 18-201 of the Delaware Limited Liability Company Act (the “Act”), the undersigned, desiring to form a limited liability company, does hereby certify as follows:

1.The name of the limited liability company is Two Rivers Physician Practices, LLC (the “Company”).

2.The address of the Company’s registered office in the State of Delaware is Corporation Trust Center, 1209 Orange Street, in the City of Wilmington, County of New Castle, Delaware 19801. The name of its registered agent at such address is The Corporation Trust Company.

3.This Certificate of Formation shall be effective upon filing with the Delaware Secretary of State.

IN WITNESS WHEREOF, the undersigned has executed this Certificate of Formation on this 21st day of October 2014.

/s/ Kathy Teague

Kathy Teague

Authorized Person