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Condensed Statements of Shareholders' Equity - USD ($)
Total
Cashless Warrants [Member]
January 2019 Financing Transaction [Member]
February 2019 Financing Transaction [Member]
January 2019 Financing Transaction Overallotment [Member]
March 2019 Financing Transaction [Member]
March 2, 2020 Financing Transaction [Member]
March 4, 2020 Financing Transaction [Member]
December 2019 Financing Transaction Overallotment [Member]
April 2020 Financing Transaction [Member]
Common Stock [Member]
Common Stock [Member]
Cashless Warrants [Member]
Common Stock [Member]
January 2019 Financing Transaction [Member]
Common Stock [Member]
February 2019 Financing Transaction [Member]
Common Stock [Member]
January 2019 Financing Transaction Overallotment [Member]
Common Stock [Member]
March 2019 Financing Transaction [Member]
Common Stock [Member]
March 2, 2020 Financing Transaction [Member]
Common Stock [Member]
March 4, 2020 Financing Transaction [Member]
Common Stock [Member]
December 2019 Financing Transaction Overallotment [Member]
Common Stock [Member]
April 2020 Financing Transaction [Member]
SeriesA Convertible Preferred Stock [Member]
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Cashless Warrants [Member]
Additional Paid-in Capital [Member]
January 2019 Financing Transaction [Member]
Additional Paid-in Capital [Member]
February 2019 Financing Transaction [Member]
Additional Paid-in Capital [Member]
January 2019 Financing Transaction Overallotment [Member]
Additional Paid-in Capital [Member]
March 2019 Financing Transaction [Member]
Additional Paid-in Capital [Member]
March 2, 2020 Financing Transaction [Member]
Additional Paid-in Capital [Member]
March 4, 2020 Financing Transaction [Member]
Additional Paid-in Capital [Member]
December 2019 Financing Transaction Overallotment [Member]
Additional Paid-in Capital [Member]
April 2020 Financing Transaction [Member]
Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2018 $ 3,042,519                   $ 46                     $ 223,500,051                   $ (220,457,578)
Beginning balance, shares at Dec. 31, 2018                     462,917                   4,417                      
Stock-based compensation expense 102,459                                         102,459                    
Shares issued upon exercise of common stock warrants 4,748                                         4,748                    
Shares issued upon exercise of common stock warrants, shares                     598                                          
Deemed dividends related to warrants downround provision                                           99,743                   (99,743)
Shares and warrants issued, net of issuance costs     $ 2,032,311 $ 6,602,735 $ 592,306 $ 7,553,793             $ 10 $ 62 $ 5 $ 59               $ 2,032,301 $ 6,602,673 $ 592,301 $ 7,553,734          
Shares and warrants issued, net of issuance costs, shares                         99,000 625,000 53,886 595,000                                
Shares issued upon conversion of preferred stock                     $ 5                     (5)                    
Shares issued upon conversion of preferred stock, shares                     50,343                   (2,278)                      
Net loss (5,916,787)                                                             (5,916,787)
Ending balance at Mar. 31, 2019 14,014,084                   $ 187                     240,488,005                   (226,474,108)
Ending balance, shares at Mar. 31, 2019                     1,886,744                   2,139                      
Beginning balance at Dec. 31, 2018 3,042,519                   $ 46                     223,500,051                   (220,457,578)
Beginning balance, shares at Dec. 31, 2018                     462,917                   4,417                      
Deemed dividends related to warrants downround provision 99,743                                                              
Net loss (19,424,558)                                                              
Ending balance at Sep. 30, 2019 7,705,458                   $ 228                     247,687,112                   (239,981,882)
Ending balance, shares at Sep. 30, 2019                     2,301,820                   2,133                      
Beginning balance at Dec. 31, 2018 3,042,519                   $ 46                     223,500,051                   (220,457,578)
Beginning balance, shares at Dec. 31, 2018                     462,917                   4,417                      
Net loss (25,100,000)                                                              
Ending balance at Dec. 31, 2019 11,200,643                   $ 547                     256,917,285                   (245,717,189)
Ending balance, shares at Dec. 31, 2019                     5,473,848                   2,133                      
Beginning balance at Mar. 31, 2019 14,014,084                   $ 187                     240,488,005                   (226,474,108)
Beginning balance, shares at Mar. 31, 2019                     1,886,744                   2,139                      
Stock-based compensation expense 224,641                                         224,641                    
Shares issued upon exercise of common stock warrants 4,845,722                   $ 41                     4,845,681                    
Shares issued upon exercise of common stock warrants, shares                     414,944                                          
Shares issued upon conversion of preferred stock, shares                     132                   (6)                      
Warrant inducement expense 1,831,116                                         1,831,116                    
Net loss (7,816,012)                                                             (7,816,012)
Ending balance at Jun. 30, 2019 13,099,551                   $ 228                     247,389,443                   (234,290,120)
Ending balance, shares at Jun. 30, 2019                     2,301,820                   2,133                      
Stock-based compensation expense 297,669                                         297,669                    
Net loss (5,691,762)                                                             (5,691,762)
Ending balance at Sep. 30, 2019 7,705,458                   $ 228                     247,687,112                   (239,981,882)
Ending balance, shares at Sep. 30, 2019                     2,301,820                   2,133                      
Beginning balance at Dec. 31, 2019 11,200,643                   $ 547                     256,917,285                   (245,717,189)
Beginning balance, shares at Dec. 31, 2019                     5,473,848                   2,133                      
Stock-based compensation expense 142,964                                         142,964                    
Shares issued upon exercise of common stock warrants 2,306,708                   $ 70 $ 61                   2,306,638 $ (61)                  
Shares issued upon exercise of common stock warrants, shares                     696,140 608,000                                        
Deemed dividends related to warrants downround provision                                           2,774                   (2,774)
Shares and warrants issued, net of issuance costs             $ 8,565,500 $ 6,093,561 $ 659,958               $ 230 $ 160 $ 19                 $ 8,565,270 $ 6,093,401 $ 659,939    
Shares and warrants issued, net of issuance costs, shares                                 2,300,000 1,600,000 192,750                          
Warrant inducement expense 2,102,109                                         2,102,109                    
Net loss (8,341,338)                                                             (8,341,338)
Ending balance at Mar. 31, 2020 22,730,105                   $ 1,087                     276,790,319                   (254,061,301)
Ending balance, shares at Mar. 31, 2020                     10,870,738                   2,133                      
Beginning balance at Dec. 31, 2019 11,200,643                   $ 547                     256,917,285                   (245,717,189)
Beginning balance, shares at Dec. 31, 2019                     5,473,848                   2,133                      
Shares issued upon exercise of common stock warrants, shares   876,772                                                            
Deemed dividends related to warrants downround provision 2,774                                                              
Net loss (19,708,975)                                                              
Ending balance at Sep. 30, 2020 21,353,297                   $ 1,340                     286,780,895                   (265,428,938)
Ending balance, shares at Sep. 30, 2020                     13,396,570                   2,133                      
Beginning balance at Mar. 31, 2020 22,730,105                   $ 1,087                     276,790,319                   (254,061,301)
Beginning balance, shares at Mar. 31, 2020                     10,870,738                   2,133                      
Stock-based compensation expense 194,236                                         194,236                    
Shares issued upon exercise of common stock warrants 72,608                   $ 2                     72,606                    
Shares issued upon exercise of common stock warrants, shares                     20,584                                          
Shares and warrants issued, net of issuance costs                   $ 9,577,297                   $ 223                     $ 9,577,074  
Shares and warrants issued, net of issuance costs, shares                                       2,230,000                        
Net loss (6,489,303)                                                             (6,489,303)
Ending balance at Jun. 30, 2020 26,084,943                   $ 1,312                     286,634,235                   (260,550,604)
Ending balance, shares at Jun. 30, 2020                     13,121,322                   2,133                      
Stock-based compensation expense 166,730                                         166,730                    
Shares issued upon exercise of common stock warrants 22,388                   $ 1 $ 27                   22,387 $ (27)                  
Shares issued upon exercise of common stock warrants, shares                     6,546 268,772                                        
Costs related to previous financings (42,430)                                         (42,430)                    
Fractional shares adjustment upon one-for-ten reverse stock split, shares                     (70)                                          
Net loss (4,878,334)                                                             (4,878,334)
Ending balance at Sep. 30, 2020 $ 21,353,297                   $ 1,340                     $ 286,780,895                   $ (265,428,938)
Ending balance, shares at Sep. 30, 2020                     13,396,570                   2,133