Exhibit 16

Joint Filing Agreement

In accordance with Rule 13d-1(k) promulgated under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them a Statement on Schedule 13D (including amendments thereto) with regard to the common stock of Transgenomic, Inc., and further agree that this Joint Filing Agreement be included as an exhibit to such joint filings. In evidence thereof, the undersigned, being duly authorized, hereby execute this agreement as of the 31st day of January, 2013.

Date:  January 31, 2013

/s/ Randal J. Kirk
Randal J. Kirk
THIRD SECURITY, LLC
By:	/s/ Randal J. Kirk
	Randal J. Kirk
	Manager
THIRD SECURITY SENIOR STAFF 2008 LLC
By:	/s/ Randal J. Kirk
	Randal J. Kirk
	Manager
THIRD SECURITY STAFF 2010 LLC
By:	/s/ Randal J. Kirk
	Randal J. Kirk
	Manager
THIRD SECURITY INCENTIVE 2010 LLC
By:	/s/ Randal J. Kirk
	Randal J. Kirk
	Manager