Delaware The First State Page 1 2723702 8100X Authentication: 203160197 SR# 20166203478 Date: 10-14-16 You may verify this certificate online at corp.delaware.gov/authver.shtml I, JEFFREY W. BULLOCK, SECRETARY OF STATE OF THE STATE OF DELAWARE, DO HEREBY CERTIFY THE ATTACHED ARE TRUE AND CORRECT COPIES OF ALL DOCUMENTS FILED FROM AND INCLUDING THE RESTATED CERTIFICATE OR A MERGER WITH A RESTATED CERTIFICATE ATTACHED OF “TRANSGENOMIC, INC.” AS RECEIVED AND FILED IN THIS OFFICE. THE FOLLOWING DOCUMENTS HAVE BEEN CERTIFIED: RESTATED CERTIFICATE, FILED THE TWENTY-SIXTH DAY OF OCTOBER, A.D. 2005, AT 10:49 O`CLOCK A.M. CERTIFICATE OF DESIGNATION, FILED THE TWENTY-EIGHTH DAY OF DECEMBER, A.D. 2010, AT 5:49 O`CLOCK P.M. CERTIFICATE OF AMENDMENT, FILED THE TWENTY-FIFTH DAY OF MAY, A.D. 2012, AT 1:18 O`CLOCK P.M. CERTIFICATE OF DESIGNATION, FILED THE TWENTY-FIFTH DAY OF MAY, A.D. 2012, AT 1:29 O`CLOCK P.M. CERTIFICATE OF AMENDMENT, FILED THE TWENTY-FOURTH DAY OF JANUARY, A.D. 2014, AT 1:22 O`CLOCK P.M.

Delaware The First State Page 2 2723702 8100X Authentication: 203160197 SR# 20166203478 Date: 10-14-16 You may verify this certificate online at corp.delaware.gov/authver.shtml CERTIFICATE OF DESIGNATION, FILED THE FIFTH DAY OF MARCH, A.D. 2014, AT 2:34 O`CLOCK P.M. CERTIFICATE OF DESIGNATION, FILED THE FIFTH DAY OF MARCH, A.D. 2014, AT 2:40 O`CLOCK P.M. CERTIFICATE OF CORRECTION, FILED THE SEVENTEENTH DAY OF FEBRUARY, A.D. 2015, AT 8 O`CLOCK A.M. CERTIFICATE OF DESIGNATION, FILED THE EIGHTH DAY OF JANUARY, A.D. 2016, AT 1:56 O`CLOCK P.M.