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STOCKHOLDERS' EQUITY (Common Stock Warrants) (Details) - $ / shares
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Jul. 07, 2015
Jun. 30, 2015
Feb. 27, 2015
Jan. 15, 2015
Dec. 31, 2014
Oct. 22, 2014
Oct. 21, 2014
Jan. 31, 2013
Jan. 24, 2013
Feb. 02, 2012
Class of Stock [Line Items]                        
Common stock warrants issued (in shares) 3,055,555 3,466,841                    
Common stock warrant, common stock called (in shares) 1,387,685 1,387,685 2,188,177 1,881,396 1,881,396 1,483,161 1,309,785 1,309,785 1,212,665 1,097,600 691,656 948,333
Warrants to purchase shares of common stock expired   431,027                    
Underlying Shares 6,696,287                      
Common stock warrant, exercise price (in usd per share) $ 10.25 $ 10.25 $ 6.50 $ 7.56 $ 7.56 $ 9.59 $ 10.86 $ 10.86 $ 11.73 $ 12.96   $ 15.00
Common Stock                        
Class of Stock [Line Items]                        
Common stock warrant, common stock called (in shares) 2,280,517                      
Various Institutional Holders; February 2017                        
Class of Stock [Line Items]                        
Underlying Shares 2,919,043                      
Common stock warrant, exercise price (in usd per share) $ 4.23                      
Affiliates of Third Security, LLC; February 2017                        
Class of Stock [Line Items]                        
Underlying Shares 443,233                      
Common stock warrant, exercise price (in usd per share) $ 4.23                      
Various Institutional Holders; January 2018                        
Class of Stock [Line Items]                        
Underlying Shares 441,655                      
Common stock warrant, exercise price (in usd per share) $ 9                      
Affiliates of Third Security, LLC; January 2018                        
Class of Stock [Line Items]                        
Common stock warrant, common stock called (in shares)                     250,000  
Underlying Shares 250,000                      
Common stock warrant, exercise price (in usd per share) $ 9                      
Various Institutional Holders; April 2020                        
Class of Stock [Line Items]                        
Underlying Shares 374,618                      
Common stock warrant, exercise price (in usd per share) $ 4                      
Various Institutional Holders; February 2020                        
Class of Stock [Line Items]                        
Underlying Shares 714,780                      
Common stock warrant, exercise price (in usd per share) $ 2.24                      
Various Institutional Holders; December 2020                        
Class of Stock [Line Items]                        
Underlying Shares 122,433                      
Common stock warrant, exercise price (in usd per share) $ 1.66                      
Various Institutional Holders; January 2021                        
Class of Stock [Line Items]                        
Underlying Shares 1,161,972                      
Common stock warrant, exercise price (in usd per share) $ 1.21                      
Affiliates of Third Security, LLC; January 2021                        
Class of Stock [Line Items]                        
Underlying Shares 161,026                      
Common stock warrant, exercise price (in usd per share) $ 1.21                      
Various Institutional Holders; January 2021                        
Class of Stock [Line Items]                        
Underlying Shares 107,527                      
Common stock warrant, exercise price (in usd per share) $ 1.21                      
Private Placement                        
Class of Stock [Line Items]                        
Common stock warrants issued (in shares) 1,174,099 800,492                    
Common stock warrant, common stock called (in shares)               365,388        
Common stock warrant, exercise price (in usd per share)               $ 4.00        
Offering                        
Class of Stock [Line Items]                        
Common stock warrants issued (in shares) 1,881,456 2,666,349