Exhibit 32.1

                         A.C. MOORE ARTS & CRAFTS, INC.

                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

     Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 (Section 1350 of
Chapter 63 of Title 18 of the United States Code), the undersigned officer of
A.C. Moore Arts & Crafts, Inc. (the "Company"), does hereby certify with respect
to this Form 10-Q of the Company for the quarterly period ended June 30, 2006
(the "Report") that:

          (1) The Report fully complies with the requirements of Section 13(a)
or 15(d) of the Securities Exchange Act of 1934; and

          (2) The information contained in the Report fairly presents, in all
material respects, the financial condition and results of operations of the
Company.


                                        /s/ Rick A. Lepley
                                        ----------------------------------------
Date: August 10, 2006                   Rick A. Lepley
                                        Chief Executive Officer

     The foregoing certification is being furnished solely pursuant to Section
906 of the Sarbanes-Oxley Act of 2002 (Section 1350 of Chapter 63 of Title 18 of
the United States Code) and is not being filed as part of the Report or as a
separate disclosure document.