Rockwell Medical, Inc. 

30142 S. Wixom Road 

Wixom, Michigan 48393 

(248) 960-9009

July 20, 2022

VIA EDGAR

Securities and Exchange Commission 

Division of Corporation Finance 

100 F Street, N.E. 

Washington, DC 20549

Attn:  Joshua Gorsky

Re: Rockwell Medical, Inc. Registration Statement on Form S-3  Filed July 14, 2022  File No. 333-266135

Ladies and Gentlemen:

In accordance with Rule 461 promulgated under the Securities Act of 1933, as amended, Rockwell Medical, Inc., a Delaware corporation (the “Company”), hereby respectfully requests that the effective time of the above referenced Registration Statement on Form S-3 filed by the Company be accelerated to 5:01 p.m., Eastern Standard Time, on July 22, 2022 or as soon thereafter as practicable.

Very truly yours,
Rockwell Medical, Inc.
By:	/s/ Russell Skibsted
Name:	Russell Skibsted
Title:	Chief Financial Officer

cc: Ryan A. Murr, Gibson, Dunn & Crutcher LLP