EXHIBIT 32.1

                    CERTIFICATIONS OF CHIEF EXECUTIVE OFFICER
                           AND CHIEF FINANCIAL OFFICER
                                   PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

         In connection with the Quarterly Report of Rockwell Medical
Technologies, Inc. (the "Company") on Form 10-QSB for the quarter ending March
31, 2004 as filed with the Securities and Exchange Commission on the date hereof
(the "Periodic Report"), I, Robert L. Chioini, Chief Executive Officer of the
Company and I, Thomas Klema, Chief Financial Officer of the Company, each
certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Sections 906
of the Sarbanes-Oxley Act of 2002, that:

         1.       the Periodic Report fully complies with the requirements of
                  Section 13(a) or 15(d) of the Securities Exchange Act of 1934;
                  and

         2.       the information contained in the Periodic Report fairly
                  presents, in all material respects, the financial condition
                  and results of operations of the Company.

Dated: May 17, 2004                                /s/ Robert L. Chioini
                                                   -----------------------------
                                                   Robert L. Chioini
                                                   Chief Executive Officer

Dated: May 17, 2004                                /s/ Thomas E. Klema
                                                   -----------------------------
                                                   Thomas E. Klema
                                                   Chief Financial Officer