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Commitments and Contingencies (Details Narrative) - USD ($)
12 Months Ended
Dec. 27, 2017
May 19, 2016
Dec. 31, 2017
Dec. 31, 2016
Oct. 04, 2017
Commitments And contingencies [Line Items]          
Rent expense     $ 287,535 $ 406,308  
Severance liability     $ 475,219    
Accrued Expenses       91,000  
Percentage of maximum compensation     35.00%    
Percentage of contribute a matching contribution     50.00%    
Percentage of eligible employee's deferral election     6.00%    
Matching contributions     $ 45,441 $ 27,163  
Plan asset value     2,200,000    
Accrued Expenses [Member]          
Commitments And contingencies [Line Items]          
Severance liability     316,812    
Other Long-term Liabilities [Member]          
Commitments And contingencies [Line Items]          
Severance liability     $ 158,407    
Dr. William Roof [Member]          
Commitments And contingencies [Line Items]          
Receive aggregate cash payments         $ 500,000
Lease Agreement [Member]          
Commitments And contingencies [Line Items]          
Lease expiration Feb. 28, 2021   Mar. 31, 2018    
Royalty and License Agreements [Member]          
Commitments And contingencies [Line Items]          
Percentage of royalties payment     0.005%    
Payment of fees     $ 2,000    
Royalty and License Agreements [Member] | Minimum [Member]          
Commitments And contingencies [Line Items]          
Gross sales     $ 2,000,000    
Royalty and License Agreements [Member] | Minimum [Member] | Former Officer [Member] | Patents [Member]          
Commitments And contingencies [Line Items]          
Percentage of royalties payment     0.0025%    
Gross sales     $ 52,000,000    
Royalty and License Agreements [Member] | Maximum [Member]          
Commitments And contingencies [Line Items]          
Gross sales     $ 52,000,000    
Executive Employment Agreement [Member] | Mr. Robert Williamsen [Member]          
Commitments And contingencies [Line Items]          
Annual base salary   $ 225,000      
Stock-based compensation   $ 149,000