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Nature of Business (Details Narrative) - USD ($)
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Dec. 31, 2016
Dec. 31, 2015
Organization, Consolidation and Presentation of Financial Statements [Abstract]        
Net loss $ 936,757 $ 2,143,491    
Net cash used in operating activities 816,963 769,212    
Cash and cash equivalents 2,303,342 $ 4,074,267 $ 3,092,172 $ 5,953,257
Accumulated deficit $ 105,339,077   $ 104,368,426