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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 LStec97BqgaXXai1V1EzMrmEW4RGRiSRnjCo/Tj3cb55/tH9Hkb34m336VYGCmgD
 jms2Zl7fbch2fmgV9OJZAQ==

<SEC-DOCUMENT>0001181431-08-050690.txt : 20080828
<SEC-HEADER>0001181431-08-050690.hdr.sgml : 20080828
<ACCEPTANCE-DATETIME>20080828194508
ACCESSION NUMBER:		0001181431-08-050690
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080828
FILED AS OF DATE:		20080828
DATE AS OF CHANGE:		20080828

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Rosen Howard B
		CENTRAL INDEX KEY:			0001307068

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33846
		FILM NUMBER:		081046840

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		650-314-3800

	MAIL ADDRESS:	
		STREET 1:		320 EAST EVELYN AVENUE
		STREET 2:		3RD FLOOR
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94041

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PHARSIGHT CORP
		CENTRAL INDEX KEY:			0001040853
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-PREPACKAGED SOFTWARE [7372]
		IRS NUMBER:				770401273
		STATE OF INCORPORATION:			CA
		FISCAL YEAR END:			0331

	BUSINESS ADDRESS:	
		STREET 1:		321 E. EVELYN AVENUE
		STREET 2:		3RD FLOOR
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94041
		BUSINESS PHONE:		6503143800

	MAIL ADDRESS:	
		STREET 1:		321 E. EVELYN AVENUE
		STREET 2:		3RD FLOOR
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94041
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd217074.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-08-28</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001040853</issuerCik>
        <issuerName>PHARSIGHT CORP</issuerName>
        <issuerTradingSymbol>PHST</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001307068</rptOwnerCik>
            <rptOwnerName>Rosen Howard B</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O PHARSIGHT CORPORATION</rptOwnerStreet1>
            <rptOwnerStreet2>321 E. EVELYN AVENUE, 3RD FLOOR</rptOwnerStreet2>
            <rptOwnerCity>MOUNTAIN VIEW</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94041</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Non-Statutory Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>4.49</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2008-08-28</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>3500</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2009-08-28</value>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2018-08-28</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>3500</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3500</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">100% of the shares subject to the option will vest and become exercisable on August 28, 2009, provided however, that the Reporting Person continues to provide service to the Issuer through such date.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Quynh Trinh, Attorney-in-fact for Howard B. Rosen</signatureName>
        <signatureDate>2008-08-28</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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