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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 D4zh2rHp5E4HHlkJA4NL25lqgp+jBI9fVUXjPyICo2rE0GKRMaRtcRy8rIWpz1q7
 jn5dR3yk5uJt04/B9dX0Hw==

<SEC-DOCUMENT>0001181431-05-046390.txt : 20050812
<SEC-HEADER>0001181431-05-046390.hdr.sgml : 20050812
<ACCEPTANCE-DATETIME>20050812113540
ACCESSION NUMBER:		0001181431-05-046390
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050811
FILED AS OF DATE:		20050812
DATE AS OF CHANGE:		20050812

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PHARSIGHT CORP
		CENTRAL INDEX KEY:			0001040853
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-PREPACKAGED SOFTWARE [7372]
		IRS NUMBER:				770401273
		STATE OF INCORPORATION:			CA
		FISCAL YEAR END:			0331

	BUSINESS ADDRESS:	
		STREET 1:		800 WEST EL CAMINO REAL
		STREET 2:		STE 200
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94040
		BUSINESS PHONE:		6503143800

	MAIL ADDRESS:	
		STREET 1:		800 WEST EL CAMINO REAL
		STREET 2:		STE 200
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94040

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Rosen Howard B
		CENTRAL INDEX KEY:			0001307068

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-31253
		FILM NUMBER:		051019779

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		650-314-3800

	MAIL ADDRESS:	
		STREET 1:		800 W. EL CAMINO REAL, SUITE 200
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94040
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd89157.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-08-11</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001040853</issuerCik>
        <issuerName>PHARSIGHT CORP</issuerName>
        <issuerTradingSymbol>PHST</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001307068</rptOwnerCik>
            <rptOwnerName>Rosen Howard B</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>800 W. EL CAMINO REAL, SUITE 200</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>MOUNTAIN VIEW</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94040</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Non-Statutory Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>2.00</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-08-11</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2006-08-11</value>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2015-08-11</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">100% of the shares subject to the option will vest and become exercisable on August 11, 2006, provided however, that the Reporting Person continues to provide service to the Issuer through such date.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Lisa Hodges, Attorney-in-fact for Howard B. Rosen</signatureName>
        <signatureDate>2005-08-12</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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