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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 LlVgx3Bna+0v3rxBxmdiH4kl2SupJ8bQc97QcKBDio0skk35m2vSf1l7Oh+ISJy7
 TgPCKc5FttQliVYqjTthyg==

<SEC-DOCUMENT>9999999997-10-010625.txt : 20100506
<SEC-HEADER>9999999997-10-010625.hdr.sgml : 20100506
<ACCEPTANCE-DATETIME>20100506114830
<PAPER>
ACCESSION NUMBER:		9999999997-10-010625
CONFORMED SUBMISSION TYPE:	ARS
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20091231
FILED AS OF DATE:		20100423
DATE AS OF CHANGE:		20100506
EFFECTIVENESS DATE:		20100423

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INSPIRE PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0001040416
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				043209022
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		ARS
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-31577
		FILM NUMBER:		10011677

	BUSINESS ADDRESS:	
		STREET 1:		4222 EMPEROR BLVD STE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703-8466
		BUSINESS PHONE:		9199419777

	MAIL ADDRESS:	
		STREET 1:		4222 EMPEROR BLVD
		STREET 2:		STE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703-8466
</SEC-HEADER>
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<TYPE>ARS
<SEQUENCE>1
<FILENAME>9999999997-10-010625.paper
<DESCRIPTION>AUTO-GENERATED PAPER DOCUMENT
<TEXT>
This document was generated as part of a paper submission.
Please reference the Document Control Number 10011677 for access to the original document.
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