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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 CWjFDG4MYcVhmSiIbwrDhKE4xOWjbDuBBwSd3pi6zCq9J29fpY9rZHfp1Np+iJ8C
 7yE+CKnHCygdNb9Tu+Zt2A==

<SEC-DOCUMENT>9999999997-09-018234.txt : 20090428
<SEC-HEADER>9999999997-09-018234.hdr.sgml : 20090428
<ACCEPTANCE-DATETIME>20090428172831
<PAPER>
ACCESSION NUMBER:		9999999997-09-018234
CONFORMED SUBMISSION TYPE:	ARS
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20081231
FILED AS OF DATE:		20090420
DATE AS OF CHANGE:		20090428
EFFECTIVENESS DATE:		20090420

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INSPIRE PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0001040416
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				043209022
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		ARS
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-31577
		FILM NUMBER:		09010637

	BUSINESS ADDRESS:	
		STREET 1:		4222 EMPEROR BLVD STE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703-8466
		BUSINESS PHONE:		9199419777

	MAIL ADDRESS:	
		STREET 1:		4222 EMPEROR BLVD
		STREET 2:		STE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703-8466
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<FILENAME>9999999997-09-018234.paper
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This document was generated as part of a paper submission.
Please reference the Document Control Number 09010637 for access to the original document.
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