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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 ChMdZTl5j7QmkAYqte83gEdS+oj2cto+alXho82Sdd50FHgue5NAZEVp0tuiUv44
 0PxIC5STVT3FwiKJQcoiKw==

<SEC-DOCUMENT>0001313617-05-000030.txt : 20050816
<SEC-HEADER>0001313617-05-000030.hdr.sgml : 20050816
<ACCEPTANCE-DATETIME>20050816135620
ACCESSION NUMBER:		0001313617-05-000030
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050812
FILED AS OF DATE:		20050816
DATE AS OF CHANGE:		20050816

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AMP-99 MANAGEMENT CO LLC
		CENTRAL INDEX KEY:			0001244765

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		051030169

	BUSINESS ADDRESS:	
		STREET 1:		AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET STE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02481-4003
		BUSINESS PHONE:		7812390700

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AMPERSAND 1999 LP
		CENTRAL INDEX KEY:			0001244768

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		051030170

	BUSINESS ADDRESS:	
		STREET 1:		AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET STE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02481-4003
		BUSINESS PHONE:		7812390700

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CHARPIE RICHARD A
		CENTRAL INDEX KEY:			0001054509

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		051030171

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		8002390706

	MAIL ADDRESS:	
		STREET 1:		C/O AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET SUITE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02181

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			V I TECHNOLOGIES INC
		CENTRAL INDEX KEY:			0001040017
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				113238476
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		5167527314

	MAIL ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-08-12</periodOfReport>

    <issuer>
        <issuerCik>0001040017</issuerCik>
        <issuerName>V I TECHNOLOGIES INC</issuerName>
        <issuerTradingSymbol>VITX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001054509</rptOwnerCik>
            <rptOwnerName>CHARPIE RICHARD A</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O AMPERSAND VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>55 WILLIAM STREET, SUITE 240</rptOwnerStreet2>
            <rptOwnerCity>WELLESLEY</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02481</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001244768</rptOwnerCik>
            <rptOwnerName>AMPERSAND 1999 LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O AMPERSAND VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>55 WILLIAM STREET, SUITE 240</rptOwnerStreet2>
            <rptOwnerCity>WELLESLEY</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02481</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001244765</rptOwnerCik>
            <rptOwnerName>AMP-99 MANAGEMENT CO LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O AMPERSAND VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>55 WILLIAM STREET, SUITE 240</rptOwnerStreet2>
            <rptOwnerCity>WELLESLEY</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02481</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2005-08-12</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>4422413</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>5869302</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>87127</value>
                    <footnoteId id="F4"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>5675720</value>
                    <footnoteId id="F5"/>
                    <footnoteId id="F6"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>12255</value>
                    <footnoteId id="F7"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">On August 12, 2005, Ampersand 1999 Limited Partnership distributed 4,333,824 shares of the issuer's common stock in a pro rata distribution to its partners for no consideration and Ampersand 1999 Companion Fund Limited Partnership distributed 88,589 shares of the issuer's common stock in a pro rata distribution to its partners for no consideration.</footnote>
        <footnote id="F2">Richard A. Charpie may be attributed with the ownership of shares beneficially owned by Ampersand 1999 Limited Partnership,  Ampersand 1999 Companion Fund Limited Partnership, Ampersand 1995 Limited Partnership, Ampersand 1995 Companion Fund Limited Partnership, Ampersand Venture Management Trust, AMP-99 Management Company Limited Liability Company (&quot;AMP-99 MC LLC&quot;) and certain shares issuable pursuant to options exercisable within 60 days of August 15, 2005 that have been assigned to one or more of the foregoing entities. Dr. Charpie disclaims beneficial ownership of all such shares except to the extent of his proportionate pecuniary interest therein.</footnote>
        <footnote id="F3">Dr. Charpie is the Principal Managing Member of AMP-99 MC LLC, which is the General Partner of Ampersand 1999 Limited Partnership and Ampersand 1999 Companion Fund Limited Partnership. Dr. Charpie is the sole member of Ampersand Venture Management 2003 LLC, which is the sole owner of shares of beneficial interest of Ampersand Venture Management Trust.  Dr. Charpie is the Managing Partner of AMP-95 MCLP LLP. AMP-95 MCLP LLP is the General Partner of AMP-95 Management Company Limited Partnership, which is the General Partner of Ampersand 1995 Limited Partnership and Ampersand 1995 Companion Fund Limited Partnership.</footnote>
        <footnote id="F4">AMP-99 MC LLC received 87,127 shares from the distribution referred to in footnote 1.  Because it had previously reported indirect beneficial ownership of these shares, these transactions constitute a mere change in form of beneficial ownership.  AMP-99 MC LLC disclaims beneficial ownership of such shares except to the extent of its proportionate pecuniary interest therein.</footnote>
        <footnote id="F5">Dr. Charpie is the beneficial owner of 9,555 shares and 2,700 shares issuable pursuant to options exercisable within 60 days of August 15, 2005.  Dr. Charpie may be attributed with the ownership of 5,426,613 shares beneficially owned by Ampersand 1999 Limited Partnership, 110,601 shares beneficially owned by Ampersand 1999 Companion Fund Limited Partnership, 38,749 shares beneficially owned by Ampersand Venture Management Trust, 87,127 shares beneficially owned by AMP-99 MC LLC and 375 shares issuable pursuant to options exercisable within 60 days of August 15, 2005 that have been assigned to one or more of the foregoing entities. Dr. Charpie disclaims beneficial ownership of all such shares except to the extent of his proportionate pecuniary interest therein.</footnote>
        <footnote id="F6">On August 12, 2005, Ampersand 1995 Limited Partnership distributed 193,333 shares of the issuer's common stock in a pro rata distribution to its partners for no consideration and Ampersand 1995 Companion Fund Limited Partnership distributed 2,745 shares of the issuer's common stock in a pro rata distribution to its partners for no consideration.</footnote>
        <footnote id="F7">Dr. Charpie received 352 shares from the distributions described in footnotes 1 and 6. Because Dr. Charpie had previously reported indirect beneficial ownership of these shares, these transactions constitute a mere change in form of beneficial ownership.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Richard A. Charpie, individually and as the Principal Managing Member of AMP-99 Management Company LLC, the General Partner of 1999 Limited Partnership</signatureName>
        <signatureDate>2005-08-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----