-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 OnYrZldRPTPCOVd1fst53D4ZfuIo8z4FcaPgAo7Pp9wcIzu0KhYFovwLrNVCXXPO
 sm3BkUDZLf89paN+X88CCw==

<SEC-DOCUMENT>0001313617-05-000018.txt : 20050505
<SEC-HEADER>0001313617-05-000018.hdr.sgml : 20050505
<ACCEPTANCE-DATETIME>20050505154314
ACCESSION NUMBER:		0001313617-05-000018
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050503
FILED AS OF DATE:		20050505
DATE AS OF CHANGE:		20050505

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AMPERSAND 1999 LP
		CENTRAL INDEX KEY:			0001244768

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		05803520

	BUSINESS ADDRESS:	
		STREET 1:		AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET STE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02481-4003
		BUSINESS PHONE:		7812390700

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AMP-99 MANAGEMENT CO LLC
		CENTRAL INDEX KEY:			0001244765

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		05803519

	BUSINESS ADDRESS:	
		STREET 1:		AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET STE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02481-4003
		BUSINESS PHONE:		7812390700

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CHARPIE RICHARD A
		CENTRAL INDEX KEY:			0001054509

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		05803521

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		8002390706

	MAIL ADDRESS:	
		STREET 1:		C/O AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET SUITE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02181

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			V I TECHNOLOGIES INC
		CENTRAL INDEX KEY:			0001040017
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				113238476
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		5167527314

	MAIL ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-05-03</periodOfReport>

    <issuer>
        <issuerCik>0001040017</issuerCik>
        <issuerName>V I TECHNOLOGIES INC</issuerName>
        <issuerTradingSymbol>VITX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001054509</rptOwnerCik>
            <rptOwnerName>CHARPIE RICHARD A</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O AMPERSAND VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>55 WILLIAM STREET, SUITE 240</rptOwnerStreet2>
            <rptOwnerCity>WELLESLEY</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02481</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001244768</rptOwnerCik>
            <rptOwnerName>AMPERSAND 1999 LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O AMPERSAND VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>55 WILLIAM STREET, SUITE 240</rptOwnerStreet2>
            <rptOwnerCity>WELLESLEY</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02481</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001244765</rptOwnerCik>
            <rptOwnerName>AMP-99 MANAGEMENT CO LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O AMPERSAND VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>55 WILLIAM STREET, SUITE 240</rptOwnerStreet2>
            <rptOwnerCity>WELLESLEY</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02481</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3.05</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-05-03</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>25000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2015-05-03</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>25000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>25000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3.05</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-05-03</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F3"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>25000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2015-05-03</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>25000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>25000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F3"/>
                    <footnoteId id="F4"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The option vests as to 25% of the total shares subject to the option on the sixth month anniversary following the date of grant and as to 25% of the total shares subject to the option on each of the second, third and fourth yearly anniversary following the date of grant.</footnote>
        <footnote id="F2">This option was granted to Dr. Charpie, a director of the issuer and the Principal Managing Member of AMP-99 Management Company Limited Liability Company, which is the General Partner of Ampersand 1999 Limited Partnership and Ampersand 1999 Companion Fund Limited Partnership.  Dr. Charpie has assigned to Ampersand 1999 Limited Partnership and Ampersand 1999 Companion Fund Limited Partnership the economic benefits of such option. Dr. Charpie and each of these venture capital funds disclaim beneficial ownership of such option except to the extent of their respective pecuniary interest therein.</footnote>
        <footnote id="F3">The option was granted to Herbert Hooper, a director of the issuer and a partner of Ampersand 1999 Limited Partnership and Ampersand 1999 Companion Fund Limited Partnership. Dr. Hooper has assigned the economic benefits of such option to Ampersand 1999 Limited Partnership and Ampersand 1999 Companion Fund Limited Partnership, both of which disclaim beneficial ownership of the option except to the extent of their pecuniary interest therein. Dr. Charpie is the Principal Managing Member of AMP-99 Management Company Limited Liability Company, which is the General Partner of Ampersand 1999 Limited Partnership and Ampersand 1999 Companion Fund Limited Partnership. Dr. Charpie disclaims beneficial ownership of the option except to the extent of his pecuniary interest therein.</footnote>
        <footnote id="F4">Dr. Charpie, a director of the issuer, is the Principal Managing Member of AMP-99 Management Company Limited Liability Company, which is the General Partner of Ampersand 1999 Limited Partnership and Ampersand 1999 Companion Fund Limited Partnership.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>Richard A. Charpie, individually and as the Principal Managing Member of AMP-99 Management Company LLC, the General Partner of 1999 Limited Partnership</signatureName>
        <signatureDate>2005-05-05</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----