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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001181431-05-045672.txt : 20050809
<SEC-HEADER>0001181431-05-045672.hdr.sgml : 20050809
<ACCEPTANCE-DATETIME>20050809214221
ACCESSION NUMBER:		0001181431-05-045672
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050805
FILED AS OF DATE:		20050809
DATE AS OF CHANGE:		20050809

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			V I TECHNOLOGIES INC
		CENTRAL INDEX KEY:			0001040017
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				113238476
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		5167527314

	MAIL ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			A.M. PAPPAS LIFE SCIENCE VENTURES I, L.P.
		CENTRAL INDEX KEY:			0001320653
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		051011702

	BUSINESS ADDRESS:	
		STREET 1:		POST OFFICE BOX 110287
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709
		BUSINESS PHONE:		(919) 998-3300

	MAIL ADDRESS:	
		STREET 1:		POST OFFICE BOX 110287
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd88691.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-08-05</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001040017</issuerCik>
        <issuerName>V I TECHNOLOGIES INC</issuerName>
        <issuerTradingSymbol>VITX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001320653</rptOwnerCik>
            <rptOwnerName>A.M. PAPPAS LIFE SCIENCE VENTURES I, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O A.M. PAPPAS &amp; ASSOCIATES, LLC</rptOwnerStreet1>
            <rptOwnerStreet2>7030 KIT CREEK ROAD</rptOwnerStreet2>
            <rptOwnerCity>RESEARCH TRIANGLE PARK</rptOwnerCity>
            <rptOwnerState>NC</rptOwnerState>
            <rptOwnerZipCode>27709</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2005-08-05</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>920148</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4367506</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The reporting person distributed 920,148 shares of the issuer's common stock held by it in a pro rata distribution to its partners on August 5, 2005 for no consideration.</footnote>
        <footnote id="F2">This amount reflects the addition of 45 shares to correct an error in the total holdings of the Fund reported on the Form 4 dated June 28, 2005.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Ford S. Worthy, Partner of A.M. Pappas &amp; Associates, LLC, the manager of AMP&amp;A Management, LLC, the general partner of A.M. Pappas Life Science Ventures, I, L.P.</signatureName>
        <signatureDate>2005-08-09</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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