-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 STISTjZk6iZTk+j+uGp0Ycme7XyE0ZVF27lDog8rbWDDABmkN6++panMADX5VkcN
 OaHr/miHplmcWBpD5uVj3Q==

<SEC-DOCUMENT>0001181431-05-018387.txt : 20050323
<SEC-HEADER>0001181431-05-018387.hdr.sgml : 20050323
<ACCEPTANCE-DATETIME>20050323192216
ACCESSION NUMBER:		0001181431-05-018387
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050321
FILED AS OF DATE:		20050323
DATE AS OF CHANGE:		20050323

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			V I TECHNOLOGIES INC
		CENTRAL INDEX KEY:			0001040017
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				113238476
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		5167527314

	MAIL ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LINSLEY ERIC W
		CENTRAL INDEX KEY:			0001320179

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		05700146

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		9199983300

	MAIL ADDRESS:	
		STREET 1:		7030 KIT CREEK ROAD
		STREET 2:		P.O. BOX 110287
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd73406.xml
<DESCRIPTION>FORM 4  FOR 3 21 05
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-03-21</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001040017</issuerCik>
        <issuerName>V I TECHNOLOGIES INC</issuerName>
        <issuerTradingSymbol>VITXD</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001320179</rptOwnerCik>
            <rptOwnerName>LINSLEY ERIC W</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>A.M. PAPPAS &amp; ASSOCIATES, LLC</rptOwnerStreet1>
            <rptOwnerStreet2>7030 KIT CREEK ROAD</rptOwnerStreet2>
            <rptOwnerCity>RESEARCH TRIANGLE PARK</rptOwnerCity>
            <rptOwnerState>NC</rptOwnerState>
            <rptOwnerZipCode>27709</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1220</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F3"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>5791572</value>
                    <footnoteId id="F3"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote 2</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">On March 21, 2005, A.M. Pappas Life Science Ventures I, L.P. (the &quot;Fund&quot;) distributed 380,000 shares of V.I. Technologies, Inc. to its partners for no consideration. The reporting person, as a limited partner, received 1,166 shares. Because the reporting person has been attributed with beneficial ownership of these shares of the issuer's stock, this transaction constitutes a mere change in the form of beneficial ownership.</footnote>
        <footnote id="F2">5,787,609 shares are directly held by A.M. Pappas Life Science Ventures I, L.P. (&quot;PV I&quot;), which has a general partner, AMP&amp;A Management, LLC (&quot;Management&quot;), which is managed by A.M. Pappas &amp; Associates, LLC (&quot;AMP&amp;A&quot;).  3,963 shares are now held directly by Management after the distribution described in footnote 1.  AMP&amp;A may be deemed a beneficial owner of these securities.  The reporting person is a member of AMP&amp;A and, as a result, may also be deemed a beneficial owner of these securities.  The reporting person disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that this person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.</footnote>
        <footnote id="F3">Reported on a post-split basis.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ John R. Barr (pursuant to power-of-attorney)</signatureName>
        <signatureDate>2005-03-23</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----