-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 CG2HrmyiC+Hx55ivITd63LZTdQ6REFKGf+VU+AkFl0miBJo+YARRPaPPmgwrcxwL
 OPxu9qEVB71fRIjQV2kElQ==

<SEC-DOCUMENT>0001180955-05-000027.txt : 20050315
<SEC-HEADER>0001180955-05-000027.hdr.sgml : 20050315
<ACCEPTANCE-DATETIME>20050315172835
ACCESSION NUMBER:		0001180955-05-000027
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050314
FILED AS OF DATE:		20050315
DATE AS OF CHANGE:		20050315

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AMPERSAND 1995 LP
		CENTRAL INDEX KEY:			0001244759

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		05682717

	BUSINESS ADDRESS:	
		STREET 1:		AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET STE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02481-4003
		BUSINESS PHONE:		7812390700

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AMP-95 MCLP LLP
		CENTRAL INDEX KEY:			0001244762

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		05682718

	BUSINESS ADDRESS:	
		STREET 1:		AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET STE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02481-4003
		BUSINESS PHONE:		7812390700

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AMP-95 MANAGEMENT CO LP
		CENTRAL INDEX KEY:			0001244757

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		05682719

	BUSINESS ADDRESS:	
		STREET 1:		AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET STE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02481-4003
		BUSINESS PHONE:		7812390700

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			V I TECHNOLOGIES INC
		CENTRAL INDEX KEY:			0001040017
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				113238476
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		5167527314

	MAIL ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-03-14</periodOfReport>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0001040017</issuerCik>
        <issuerName>V I TECHNOLOGIES INC</issuerName>
        <issuerTradingSymbol>VITX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001244757</rptOwnerCik>
            <rptOwnerName>AMP-95 MANAGEMENT CO LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O AMPERSAND VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>55 WILLIAM STREET, SUITE 240</rptOwnerStreet2>
            <rptOwnerCity>WELLESLEY</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02481</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001244762</rptOwnerCik>
            <rptOwnerName>AMP-95 MCLP LLP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O AMPERSAND VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>55 WILLIAM STREET, SUITE 240</rptOwnerStreet2>
            <rptOwnerCity>WELLESLEY</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02481</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001244759</rptOwnerCik>
            <rptOwnerName>AMPERSAND 1995 LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O AMPERSAND VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>55 WILLIAM STREET, SUITE 240</rptOwnerStreet2>
            <rptOwnerCity>WELLESLEY</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02481</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2005-03-14</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>5111469</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1960784</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>101722</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2005-03-14</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F3"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>101722</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F3"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">AMP-95 MCLP LLP is the general partner of AMP-95 Management Company Limited Partnership (&quot;AMP-95 MCLP&quot;), which is the general partner of Ampersand 1995 Limited Partnership and Ampersand 1995 Companion Fund Limited Partnership.  AMP-95 MCLP LLP and AMP-95 MCLP each has been attributed with the beneficial ownership of shares of the issuer's common stock held by Ampersand 1995 Limited Partnership and Ampersand 1995 Companion Fund Limited Partnership and each disclaims beneficial ownership of all such shares except to the extent of its proportionate pecuniary interest therein.  Ampersand 1995 Limited Partnership distributed 5,029,687 shares of the issuer's common stock held by it in a pro-rata distribution to its partners on March 14, 2005.  Ampersand 1995 Companion Fund Limited Partnership distributed 81,782 shares of the issuer's common stock held by it in a pro-rata distribution to its partners on March 14, 2005.</footnote>
        <footnote id="F2">AMP-95 MCLP received 101,722 shares from the distributions described in footnote 1.  Because AMP-95 MCLP had previously reported indirect beneficial ownership of these shares, these transactions constitute a mere change in form of beneficial ownersip.  AMP-95 MCLP LLP is the general partner of AMP-95 MCLP and may be attributed with the beneficial ownership of such shares.  AMP-95 MCLP LLP disclaims beneficial ownership of all such shares except to the extent of its proportionate pecuniary interest therein.</footnote>
        <footnote id="F3">AMP-95 MCLP distributed all of the shares described in footnote 2 to its partners on March 14, 2005 for no consideration.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>Richard A. Charpie, as Managing Partner of AMP-95 MCLP LLP, the General Partner of AMP-95 MCLP</signatureName>
        <signatureDate>2005-03-14</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----