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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 sF/XxCrKT9FuxAkwD3hW5g==

<SEC-DOCUMENT>0001180955-03-000024.txt : 20030606
<SEC-HEADER>0001180955-03-000024.hdr.sgml : 20030606
<ACCEPTANCE-DATETIME>20030605175431
ACCESSION NUMBER:		0001180955-03-000024
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20030603
FILED AS OF DATE:		20030606

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			V I TECHNOLOGIES INC
		CENTRAL INDEX KEY:			0001040017
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				113238476
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		5167527314

	MAIL ADDRESS:	
		STREET 1:		134 COOLIDGE AVE
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CHARPIE RICHARD A
		CENTRAL INDEX KEY:			0001054509

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24241
		FILM NUMBER:		03734672

	BUSINESS ADDRESS:	
		STREET 1:		C/O AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET SUITE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02181
		BUSINESS PHONE:		8002390706

	MAIL ADDRESS:	
		STREET 1:		C/O AMPERSAND VENTURES
		STREET 2:		55 WILLIAM STREET SUITE 240
		CITY:			WELLESLEY
		STATE:			MA
		ZIP:			02181
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>
    <schemaVersion>X0101</schemaVersion>

    <documentType>4</documentType><periodOfReport>2003-06-03</periodOfReport>
    <issuer>
        <issuerCik>0001040017</issuerCik>
        <issuerName>V I TECHNOLOGIES INC</issuerName>
        <issuerTradingSymbol>VITX</issuerTradingSymbol></issuer><reportingOwner><reportingOwnerId>
            <rptOwnerCik>0001054509</rptOwnerCik>
            <rptOwnerName>CHARPIE RICHARD A</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>  </rptOwnerStreet1>
            <rptOwnerStreet2>  </rptOwnerStreet2>
            <rptOwnerCity>  </rptOwnerCity>
            <rptOwnerState>  </rptOwnerState>
            <rptOwnerZipCode>  </rptOwnerZipCode>
        </reportingOwnerAddress>
            <reportingOwnerRelationship>
<isDirector>1</isDirector><isOfficer>0</isOfficer><isTenPercentOwner>1</isTenPercentOwner><isOther>0</isOther></reportingOwnerRelationship></reportingOwner><nonDerivativeSecurity><securityTitle><value>Common Stock</value></securityTitle><transactionDate><value>2003-06-03</value></transactionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>P</transactionCode><equitySwapInvolved>0</equitySwapInvolved></transactionCoding><transactionAmounts><transactionShares><value>5882353</value></transactionShares><transactionValue><value>1.02</value></transactionValue><transactionAcquiredDisposedCode><value>A</value></transactionAcquiredDisposedCode></transactionAmounts><postTransactionAmounts><sharesOwnedFollowingTransaction><value>15645383</value></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrIndirectOwnership><value>I</value></directOrIndirectOwnership><natureOfOwnership><value>(1), (2), (3) and (4)</value><footnoteId id="F1"/><footnoteId id="F2"/>
<footnoteId id="F3"/><footnoteId id="F4"/></natureOfOwnership></ownershipNature></nonDerivativeSecurity><footnotes><footnote id="F1">Pursuant to a rights offering by the issuer, Ampersand 1995 Limited Partnership (f/k/a Ampersand Specialty Materials and Chemicals III Limited Partnership) acquired 1,933,333 shares of the issuer's common stock, Ampersand 1995 Companion Fund Limited Partnership (f/k/a Ampersand Specialty Materials and Chemicals III Companion Fund Limited Partnership) acquired 27,451 shares of the issuer's common stock, Ampersand 1999 Limited Partnership (f/k/a Ampersand IV Limited Partnership) acquired 1,181,765 shares of the issuer's common stock, and Ampersand 1999 Companion Fund Limited Partnership (f/k/a Ampersand IV Companion Fund Limited Partnership) acquired 24,118 shares of the issuer's common stock.</footnote><footnote id="F2">Richard A. Charpie may be attributed with the ownership of 6,963,020 shares held by Ampersand 1995 Limited Partnership, 109,233 shares held by Ampersand 1995 Com
panion Fund Limited Partnership, 2,161,765 shares held by Ampersand 1999 Limited Partnership, 44,118 shares held by Ampersand 1999 Companion Fund Limited Partnership, 331,487 shares held by Ampersand 1994 Limited Partnership (f/k/a Laboratory Partners I Limited Partnership), 142,065 shares held by Ampersand 1994 Companion Fund Limited Partnership (f/k/a Laboratory Partners Companion Fund Limited Partnership), 11,342 shares held by Ampersand Venture Management LLC and 5,882,353 shares held by Precision Pharma Services, Inc.</footnote><footnote id="F3"> Dr. Charpie is the Managing Partner of AMP-95 MCLP LLP.  AMP-95 MCLP LLP is the General Partner of AMP-95 Management Company Limited Partnership, which is the General Partner of Ampersand 1995 Limited Partnership and Ampersand 1995 Companion Fund Limited Partnership.  Dr. Charpie is the Principal Managing Member of AMP-99 Management Company Limited Liability Company (f/k/a AMP-IV Management Company Limited Liability Company), which is the General Partner of Amp
ersand 1999 Limited Partnership and Ampersand 1999 Companion Fund Limited Partnership.  Dr. Charpie is the Managing Partner of AMP-94 MCLP LLP (f/k/a Ampersand Lab Partners MCLP LLP).  AMP-94 MCLP LLP is the General Partner of AMP-94 Management Company Limited Partnership (f/k/a Ampersand Lab Partners Management Company Limited Partnership), which is the General Partner of Ampersand 1994 Limited Partnership and Ampersand 1994 Companion Fund Limited Partnership. </footnote><footnote id="F4">Dr. Charpie is the sole owner of shares of beneficial interest of Ampersand Venture Management Trust, which is the sole member of Ampersand Venture Management LLC.  Ampersand 1999 Limited Partnership, Ampersand 1999 Companion Fund Limited Partnership, Ampersand 2001 Limited Partnership and Ampersand 2001 Companion Fund Limited Partnership own 95.7% of Precision Pharma Services, Inc.  Dr. Charpie disclaims beneficial ownership of all of these shares except to the extent of his proportionate pecuniary interest therein.  </fo
otnote></footnotes><ownerSignature><signatureName>Richard A. Charpie</signatureName><signatureDate>2003-06-05</signatureDate></ownerSignature></ownershipDocument>

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