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Commitments and contingencies - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Nov. 13, 2015
Apr. 06, 2015
Jan. 02, 2013
Jan. 31, 2015
Oct. 31, 2013
Jul. 31, 2013
Dec. 31, 2012
May. 31, 2011
Apr. 30, 2010
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
Dec. 31, 2014
Loss Contingencies [Line Items]                            
Operating Leases, Rent Expense                   $ 96,000 $ 80,000 $ 268,000 $ 230,000  
Property Under Commercial Lease And Sublease Details                       On February 7, 2014, the Company entered into the Second Amendment to Commercial Lease which, among other things a) extended the term of the lease from March 31, 2014 to March 31, 2017; b) reduced the 19,000 square feet, the amount of space under the master lease, by approximately 6,011 square feet, to approximately 13,000 square feet, which is the amount of space the Company currently occupies    
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Grants In Period, Gross         675,000                  
Granted, Weighted Avg.Exercise Price                       $ 0.17 $ 0.35  
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price                   $ 0.34 $ 0.71 $ 0.34 $ 0.71  
Operating Leases Base rent In Year Two                       2.06%    
Operating Leases Base Rent In Year Three                       2.06%    
Dr. Kornman [Member]                            
Loss Contingencies [Line Items]                            
Officers' Compensation                       $ 360,000    
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Grants In Period, Gross       2,030,000 2,250,000   300,000 100,000 30,000          
Granted, Weighted Avg.Exercise Price       $ 0.26 $ 0.3799                  
Annual Reimbursement For Payment Of Life Insurance Premiums                       3,296    
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price             $ 0.34 $ 0.46 $ 0.745          
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage         2.08%     25.00% 20.00%          
Dr. Kornman [Member] | First Anniversaries [Member]                            
Loss Contingencies [Line Items]                            
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage         25.00%   25.00%              
Dr. Kornman [Member] | Second Anniversaries [Member]                            
Loss Contingencies [Line Items]                            
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage             33.00%              
Dr. Kornman [Member] | Third Anniversaries [Member]                            
Loss Contingencies [Line Items]                            
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage             42.00%              
Chief Marketing Officer [Member]                            
Loss Contingencies [Line Items]                            
Officers' Compensation             $ 265,000              
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Grants In Period, Gross     200,000 660,000                    
Granted, Weighted Avg.Exercise Price     $ 0.29 $ 0.26                    
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage         2.08%                  
Maximum Percentage Of Bonus On Annual Salary             30.00%              
Maximum Reimbursement Expenses           $ 60,000 $ 34,000           $ 16,000  
Travel and Entertainment Expense                       $ 40,000   $ 80,000
Chief Marketing Officer [Member] | First Anniversaries [Member]                            
Loss Contingencies [Line Items]                            
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Number of Shares     50,000                      
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage         25.00%                  
Chief Marketing Officer [Member] | Second Anniversaries [Member]                            
Loss Contingencies [Line Items]                            
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Number of Shares     66,000                      
Chief Marketing Officer [Member] | Third Anniversaries [Member]                            
Loss Contingencies [Line Items]                            
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Number of Shares     84,000                      
Subsequent Event [Member]                            
Loss Contingencies [Line Items]                            
Shares Unvested Related Shares Granted 84,000                          
Chief Executive Officer [Member]                            
Loss Contingencies [Line Items]                            
Officers' Compensation   $ 365,000                        
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Grants In Period, Gross   14,245,227                        
Granted, Weighted Avg.Exercise Price   $ 0.1525                        
Percentage Of Bonus On Base Salary For Executives   35.00%                        
Percentage Of Stretch Bonus Of Target Bonus   150.00%                        
Percentage Of Shares To Be Vest   25.00%                        
Percentage Of Additional Shares To Be Vest   2.083%