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Commitments and contingencies - Additional Information (Detail) (USD $)
3 Months Ended 6 Months Ended 5 Months Ended 0 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Dec. 31, 2014
Subsequent Event [Member]
Oct. 22, 2013
Dr. Kornman [Member]
Oct. 22, 2013
Mr. Lurier [Member]
Oct. 22, 2013
Scott Snyder [Member]
Jun. 30, 2014
Scott Snyder [Member]
Dec. 31, 2013
Scott Snyder [Member]
Jan. 02, 2013
Scott Snyder [Member]
Jan. 02, 2013
Installment One [Member]
Scott Snyder [Member]
Jan. 02, 2013
Installment Two [Member]
Scott Snyder [Member]
Jan. 02, 2013
Installment Three [Member]
Scott Snyder [Member]
Loss Contingencies [Line Items]                            
Executive bonus to base salary percentage                     30.00%      
Granted,share           2,250,000 750,000 675,000 200,000          
Granted,weighted avg.exercise price     $ 0.35 $ 0.29   $ 0.3799 $ 0.3799 $ 0.3799 $ 0.29          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number                       50,000 66,000 84,000
Basic Salary                     $ 265,000      
Reimbursement expenditure maximum                   34,000        
Additional reimbursement expenditure     16,000   20,000                  
Operating Leases, Rent Expense $ 79,000 $ 81,000 $ 150,000 $ 161,000                    
Property Under Commercial Lease And Sublease Details     On February 7, 2014, the Company entered into the Second Amendment to Commercial Lease which, among other things, extends the term of the lease from March 31, 2014 to March 31, 2017 and reduced the 19,000 square feet, the amount of space under the master lease, by approximately 6,011 square feet, to approximately 13,000 square feet, the current space the Company occupies. In May 2010, the Company completed a sublease of the 6,011 square feet of underutilized office and laboratory space.