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Provision for income taxes (Detail)
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Tax at statutory rate (34.00%) (34.00%)
State taxes, net of federal benefit 0.00% 0.00%
Research and development credit (1.70%) 0.10%
Share based payment expense 0.70% 0.90%
Other 3.00% 1.40%
Removal of deferred tax asset on federal net operating losses 64.10% 26.90%
Establishment of deferred tax asset on state net operating losses and state deferred taxes, net of federal income tax benefit 6.40% (9.60%)
Change in valuation allowance (38.60%) 14.30%
Effective tax rate 0.00% 0.00%