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Taxes Effective Tax Rate Reconciliation (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Abstract]      
Effective Tax Rate Reconciliation, Excess Tax Benefits $ (28,279) $ (13,836) $ (35,171)
Effect of Biotix contingent consideration gain 0 (4,394) 0
Income Tax Expense (Benefit), at Federal Statutory Income Tax Rate 143,092 136,890 200,978
State and Local Income Taxes 499 2,787 376
Deferred Tax Benefit, net related to Swiss Tax Reform (15,833) 0 0
Provisional one-time charge on US tax reform 0 3,597 71,982
Foreign Income Tax Rate Differential 18,546 12,710 (43,691)
Other Adjustments 2,260 1,493 3,776
Provision for taxes $ 120,285 $ 139,247 $ 198,250
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent   35.00% 35.00%