0001279569-18-001260.txt : 20180606 0001279569-18-001260.hdr.sgml : 20180606 20180606131302 ACCESSION NUMBER: 0001279569-18-001260 CONFORMED SUBMISSION TYPE: 6-K PUBLIC DOCUMENT COUNT: 3 CONFORMED PERIOD OF REPORT: 20180606 FILED AS OF DATE: 20180606 DATE AS OF CHANGE: 20180606 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Correvio Pharma Corp. CENTRAL INDEX KEY: 0001036141 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 000000000 STATE OF INCORPORATION: A1 FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 6-K SEC ACT: 1934 Act SEC FILE NUMBER: 000-29338 FILM NUMBER: 18883466 BUSINESS ADDRESS: STREET 1: 6TH FLOOR STREET 2: 1441 CREEKSIDE DRIVE CITY: VANCOUVER STATE: A1 ZIP: V6J 4S7 BUSINESS PHONE: 1-604-677-6905 MAIL ADDRESS: STREET 1: 6TH FLOOR STREET 2: 1441 CREEKSIDE DRIVE CITY: VANCOUVER STATE: A1 ZIP: V6J 4S7 FORMER COMPANY: FORMER CONFORMED NAME: Cardiome Pharma Corp DATE OF NAME CHANGE: 20040625 FORMER COMPANY: FORMER CONFORMED NAME: CARDIOME PHARMA CORP DATE OF NAME CHANGE: 20000407 6-K 1 correvio6k.htm FORM 6-K

 

 

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

FORM 6-K

 

Report of Foreign Private Issuer

Pursuant to Rule 13A-16 or 15d-16 of

The Securities Exchange Act of 1934

 

For the month of June 2018

 

COMMISSION FILE Number. 000-29338

 

CORREVIO PHARMA CORP.

 

(Translation of registrant’s name into English)

 

1441 Creekside Drive, 6th floor

Vancouver, British Columbia, V6J 4S7, CANADA

 

(Address of principal executive offices)

 

 

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F

 

Form 20-F ☒ Form 40-F ☐

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ☐

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ☐

  

 

 

 
 

 

 

DOCUMENTS INCLUDED AS PART OF THIS REPORT

 

Exhibit   Description
     
99.1   News release dated June 6, 2018 - Brinavess Data Receives Top Award For Best Article Published In The Spanish Medical Journal EMERGENCIAS

  

 

 

 

 

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

  CORREVIO PHARMA CORP.
  (Registrant)
     
Date: June 6, 2018 By: /s/ Justin Renz
    Name: Justin Renz
    Title: Chief Financial Officer

 

 

 


 EX-99.1 2 ex991.htm NEWS RELEASE DATED JUNE 6, 2018

Exhibit 99.1

 

 

Brinavess Data Receives Top Award For Best Article Published In The Spanish Medical Journal EMERGENCIAS

NASDAQ: CORV, TSX: CORV

Article Awarded the 10th Luis Jimenez Murillo Prize, Which Will Be Presented During Ceremony at SEMES 2018 in Toledo, Spain

VANCOUVER, June 6, 2018 /CNW/ - Correvio Pharma Corp. (NASDAQ:CORV / TSX:CORV), a revenue-generating, specialty pharmaceutical company focused on commercializing hospital drugs, today announced that the Brinavess® study, titled "Vernakalant in hospital emergency practice: safety and effectiveness," published by Jose Carbajosa Dalmau (Alicante, Spain), was awarded first prize for the best work published during the year 2017 in the medical journal EMERGENCIAS, a prestigious, emergency room focused medical journal in Spain.  The award will be presented to Dr. Carbajosa Dalmau at a ceremony at the Spanish Society of Emergency Medicine (SEMES) 30th National Congress 2018, being held June 6-8, 2018 in Toledo, Spain.

"We are honored to see that this Brinavess study was selected to receive the award from the SEMES and believe it underscores Brinavess' importance for patients where pharmacologic cardioversion is appropriate," said Kiran Bhirangi, M.D., Correvio's Vice President, Clinical Development and Medical Affairs. "Brinavess is currently marketed in 33 countries across the globe and has repeatedly demonstrated its ability to rapidly induce cardioversion in real-world clinical practice."

This prospective multicenter study (Carbajosa Dalmau, et al. 2017) investigated the safety and effectiveness of Brinavess (vernakalant hydrochloride, IV) for the rapid conversion of recent onset atrial fibrillation (AF), in routine hospital emergency department care in Spain, and assessed factors associated with a more effective response.  The study evaluated 165 cases where patients were administered Brinavess for pharmacologic cardioversion of AF between September 2014 and March 2016 in 5 hospitals in Valencia, Spain.  The data demonstrated that cardioversion with Brinavess was effective in 77.6% (95% CI, 71.1%–84%) of cases.  The median time to conversion was 8 minutes (range 6-12 minutes) after the first dose and 34 minutes (range 22-62 minutes) after a second dose.  There was a statistically significant association between AF duration of less than 12 hours and greater effectiveness of Brinavess (83.6% versus 59.5%; adjusted odds ratio, 2.76; 95% CI, 1.12 – 6.80; p=0.03).  Adverse events were reported for 30 patients (18%).  None of the events had clinically important consequences, and only 2 cases (1.2%) required suspension of treatment.

A copy of this previously published Brinavess study can be accessed online here.

About Atrial Fibrillation

Atrial Fibrillation (also known as AFib or AF) is a supraventricular tachyarrhythmia with uncoordinated atrial activation resulting in ineffective atrial contraction and if left untreated, structural and/or electrophysiological atrial tissue abnormalities.1 AF is a common cardiac rhythm disturbance that increases in prevalence with advancing age.1 According to the American Heart Association, estimates of the prevalence of AF in the U.S. ranged from 2.7 million to 6.1 million in 2010, and is expected to rise to between 5.6 million to 12 million in 2030.2 There are two strategies to manage AF, namely, rhythm- or rate-control. A rhythm-control strategy may be used in patients who are severely compromised, remain symptomatic despite adequate rate control, when adequate rate control is difficult to achieve, when long term rhythm control therapy is preferred, younger patient age, presence of tachycardia-mediated cardiomyopathy, and first episode of AF.1,3 Early intervention with a rhythm-control strategy to prevent progression of AF may be particularly beneficial to the AF patient.1

About BRINAVESS®

Brinavess® (vernakalant HCl, IV) is an antiarrhythmic drug that acts preferentially in the atria by prolonging atrial refractoriness and slowing impulse conduction in a rate-dependent fashion. Brinavess is approved for marketing in Europe, Canada and several other countries worldwide. In Europe, it is approved for the rapid conversion of recent onset atrial fibrillation to sinus rhythm in adults: 1) for non-surgery patients: atrial fibrillation < 7 days duration; and 2) for post-cardiac surgery patients: atrial fibrillation < 3 days duration. Vernakalant IV is not approved for use in the United States.

References

  1. January CT et al. 2014 AHA/ACC /HRS guideline for the management of patients with atrial fibrillation. J AM Coll Cardiol. 2014;34:e1-e76.
  2. Mozaffarian D et al. Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation. 2016 Jan 26;133(4):e38-60.
  3. Kirchhof P et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS European Heart Journal (2016) 37, 2893–2962.
  4. Carbajosa Dalmau J, et al. Seguridad y eficacia de vernakalant en la practica clínica de los servicios de urgencias [Vernakalant in hospital emergency practice: safety and effectiveness]. Emergencias 2017;29:397-402

About Correvio Pharma Corp.

Correvio Pharma Corp. is a revenue-generating, specialty pharmaceutical company focused on providing innovative, high-quality brands that meet the needs of acute care physicians and patients. With a commercial presence and distribution network covering over 60 countries worldwide, Correvio develops, acquires and commercializes brands for the in-hospital, acute care market segment. The Company's portfolio of approved and marketed brands includes: Xydalba™ (dalbavancin hydrochloride), for the treatment of acute bacterial skin and skin structure infections (ABSSSI); Zevtera®/Mabelio® (ceftobiprole medocaril sodium), a cephalosporin antibiotic for the treatment of community- and hospital-acquired pneumonia (CAP, HAP); Brinavess® (vernakalant IV) for the rapid conversion of recent onset atrial fibrillation to sinus rhythm; Aggrastat® (tirofiban hydrochloride) for the reduction of thrombotic cardiovascular events in patients with acute coronary syndrome, and Esmocard® and Esmocard Lyo® (esmolol hydrochloride), a short-acting betablocker used to control rapid heart rate in a number of cardiovascular indications. Correvio's pipeline of product candidates includes Trevyent®, a drug device combination that is designed to deliver treprostinil, the world's leading treatment for pulmonary arterial hypertension.  

Correvio is traded on the NASDAQ Capital Market (CORV) and the Toronto Stock Exchange (CORV). For more information, please visit our web site www.correvio.com.

Forward-Looking Statement Disclaimer

Certain statements in this news release contain forward-looking statements within the meaning of the U.S. Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation ("forward-looking statements") that may not be based on historical fact, including without limitation statements containing the words "believe", "may", "plan", "will", "estimate", "continue", "anticipate", "intend", "expect" and similar expressions. Such forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the actual results, events or developments to be materially different from any future results, events or developments expressed or implied by such forward-looking statements. A discussion of the risks and uncertainties facing Correvio are discussed in the most recent annual and quarterly reports of our former parent company Cardiome Pharma Corp., and detailed from time to time in our other filings with the Securities and Exchange Commission ("SEC") available at www.sec.gov and the Canadian securities regulatory authorities at www.sedar.com. All of the risks and certainties disclosed in these filings are hereby incorporated by reference in their entirety. While Correvio makes these forward-looking statements in good faith, given these risks, uncertainties and factors, you are cautioned not to place undue reliance on any forward-looking statements made in this press release. All forward-looking statements made herein are based on our current expectations and we undertake no obligation to revise or update such forward-looking statements to reflect subsequent events or circumstances, except as required by law.

Correvio® and the Correvio Logo are the proprietary trademarks of Correvio Pharma Corp.
Aggrastat® and Brinavess® are trademarks owned by Correvio and its affiliates worldwide.
Xydalba™ is a trademark of Allergan Pharmaceuticals International Limited, and used under license.
Zevtera® and Mabelio® are trademarks owned by Basilea Pharmaceutica International Ltd., and used under license.
Esmocard® and Esmocard Lyo® are trademarks owned by Orpha-Devel Handels und Vertriebs GmbH, and used under license.
Trevyent® is a trademark of SteadyMed and used under license.
All other trademarks are the property of their respective owners.

View original content:http://www.prnewswire.com/news-releases/brinavess-data-receives-top-award-for-best-article-published-in-the-spanish-medical-journal-emergencias-300660446.html

SOURCE Correvio Pharma Corp

View original content: http://www.newswire.ca/en/releases/archive/June2018/06/c4989.html

%CIK: 0001036141

For further information: Justin Renz, CFO, Correvio Pharma Corp., 604.677.6905 ext. 128, 800.330.9928, jrenz@correvio.com; Argot Partners, Michelle Carroll, 212.600.1902, michelle@argotpartners.com

CO: Correvio Pharma Corp

CNW 08:00e 06-JUN-18

 

 

 

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