Exhibit 99.1

Form 51-102F3

MATERIAL CHANGE REPORT

Item 1.	Name and Address of Reporting Issuer
	Cardiome Pharma Corp. (“Cardiome” or the “Corporation”) 6190 Agronomy Rd, Suite 405 Vancouver, BC V6T 1Z3
Item 2.	Date of Material Change
	July 18, 2014
Item 3.	News Release
	July 18, 2014 – Vancouver, Canada.
Item 4.	Summary of Material Change
	Cardiome announced today the closing of a senior secured term loan facility of up to $22 million.
Item 5.	5.1 - Full Description of Material Change
	See attached press release.
	5.2 – Disclosure for Restructuring Transactions
	Not applicable.
Item 6.	Reliance on subsection 7.1(2) of National Instrument 51-102
	Not applicable.
Item 7.	Omitted Information
	Not applicable.
Item 8.	Executive Officer
	Jennifer Archibald, Chief Financial Officer
	Telephone: 604-677-6905.
Item 9.	Date of Report
	This Material Change Report is dated July 18, 2014.