Note 5 - Intangible Assets, Net - Intangible Assets (Details) - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Cost	$ 2,688,343	$ 1,644,308
Accumulated Amortization	1,957,508	1,546,383
Net Book Value	730,835	97,925
eClinical Customer List [Member]
Cost	1,392,701	1,392,701
Accumulated Amortization	1,392,701	1,392,701
Net Book Value	$ 0	0
Finite-Lived Intangible Asset, Useful Life	3 years
Promasys B.V. Customer List [Member]
Cost	$ 113,220	118,780
Accumulated Amortization	113,220	32,994
Net Book Value	$ 0	85,786
Finite-Lived Intangible Asset, Useful Life	15 years
Promasys B.V. Software Code [Member]
Cost	$ 72,837	72,837
Accumulated Amortization	72,837	60,698
Net Book Value	$ 0	12,139
Finite-Lived Intangible Asset, Useful Life	5 years
Promasys B.V. URLs/Website [Member]
Cost	$ 57,182	59,990
Accumulated Amortization	57,182	59,990
Net Book Value	$ 0	0
Finite-Lived Intangible Asset, Useful Life	3 years
Acuity Software Code [Member]
Cost	$ 1,052,403	0
Accumulated Amortization	321,568	0
Net Book Value	$ 730,835	$ 0
Finite-Lived Intangible Asset, Useful Life	3 years