Note 6 - Accounts Payable and Accrued Expenses - Accounts Payable and Accrued Expenses (Details) - USD ($)	Dec. 31, 2017	Dec. 31, 2016
Accounts payable	$ 1,303,073	$ 697,060
Accrued payroll and related costs	925,890	886,334
Other accrued expenses	184,131	431,961
Accrued interest	172,951	107,718
Total accounts payable and accrued expenses	$ 2,586,045	$ 2,123,073