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Note 5 - Intangible Assets, Net - Intangible Assets (Details) - USD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Cost $ 1,644,308 $ 1,622,309
Accumulated Amortization 1,546,383 1,513,429
Net Book Value 97,925 108,880
eClinical Customer List [Member]    
Cost 1,392,701 1,392,701
Accumulated Amortization 1,392,701 1,392,701
Net Book Value $ 0 0
Finite-Lived Intangible Asset, Useful Life 3 years  
Promasys B.V. Customer List [Member]    
Cost $ 118,780 104,163
Accumulated Amortization 32,994 21,990
Net Book Value $ 85,786 82,173
Finite-Lived Intangible Asset, Useful Life 15 years  
Promasys B.V. Software Code [Member]    
Cost $ 72,837 72,837
Accumulated Amortization 60,698 46,130
Net Book Value $ 12,139 26,707
Finite-Lived Intangible Asset, Useful Life 5 years  
Promasys B.V. URLs/Website [Member]    
Cost $ 59,990 52,608
Accumulated Amortization 59,990 52,608
Net Book Value $ 0 $ 0
Finite-Lived Intangible Asset, Useful Life 3 years