Exhibit 21.1

LIST OF SUBSIDIARIES

Luminex International, Inc., a Delaware corporation

Luminex B.V., a Netherlands Private Company with limited liability

Luminex 2 B.V., a Netherlands Private Company with limited liability

Luminex 3 B.V., a Netherlands Private Company with limited liability

Luminex Debt Holding, LLC, a Delaware limited liability company

Nanosphere, LLC, a Delaware limited liability company

Luminex Molecular Diagnostics, Inc., an Ontario, Canadian corporation

Luminex Trading (Shanghai) Company Limited, a limited liability company under the laws of the PRC

Luminex Japan Corporation Ltd., a Japanese KK

Labpac Pty Ltd, an Australian Proprietary company, limited by shares

Luminex Hong Kong Limited, a Hong Kong company limited by shares

ChandlerTec, LLC, a Delaware limited liability company

Iris Biotech, LLC, a Delaware limited liability company

Amnis, LLC, a Delaware limited liability company

Luminex London Ltd., a private limited company under the laws of England and Wales

Luminex Munich GmbH, a German limited liability company

Luminex Paris Sas, a French simplified joint stock company