The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACLARIS THERAPEUTICS INC COM 00461U105 7,350 408,329 SH   SOLE   408,329 0 0
ALLENA PHARMACEUTICALS COM 018119107 3,005 3,330,373 SH   SOLE   3,330,373 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 18,906 1,771,844 SH   SOLE   1,771,844 0 0
ANAPTYSBIO INC COM 032724106 24,400 899,700 SH   SOLE   899,700 0 0
APTINYX INC COM 03836N103 4,407 1,883,244 SH   SOLE   1,883,244 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 201,494 8,434,232 SH   SOLE   8,434,232 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 23,126 3,530,657 SH   SOLE   3,530,657 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 9,328 951,814 SH   SOLE   951,814 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 2,649 433,247 SH   SOLE   433,247 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 18,419 442,880 SH   SOLE   442,880 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 21,334 1,671,918 SH   SOLE   1,671,918 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 17,920 851,306 SH   SOLE   851,306 0 0
EPIZYME INC COM 29428V104 3,786 739,369 SH   SOLE   739,369 0 0
ESSA PHARMA INC COM NEW 29668H708 2,867 358,346 SH   SOLE   358,346 0 0
FRAZIER LIFESCIENCES ACQU CO UNIT 12/09/2025 G3710A121 15,055 1,501,000 SH   SOLE   1,501,000 0 0
FREELINE THERAPEUTICS HLDGS SPONSORED ADS 35655L107 1,876 550,000 SH   SOLE   550,000 0 0
GALERA THERAPEUTICS INC COM 36338D108 1,952 241,000 SH   SOLE   241,000 0 0
GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 11,812 851,638 SH   SOLE   851,638 0 0
GRITSTONE BIO INC COM 39868T105 50,406 4,667,242 SH   SOLE   4,667,242 0 0
IMAGO BIOSCIENCES INC COM 45250K107 59,515 2,971,274 SH   SOLE   2,971,274 0 0
IMMUNOVANT INC COM 45258J102 5,090 585,759 SH   SOLE   585,759 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 65,948 2,674,299 SH   SOLE   2,674,299 0 0
IVERIC BIO INC COM 46583P102 29,856 1,838,402 SH   SOLE   1,838,402 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 2,736 156,807 SH   SOLE   156,807 0 0
KRYSTAL BIOTECH INC COM 501147102 40,267 771,250 SH   SOLE   771,250 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 71,053 3,566,912 SH   SOLE   3,566,912 0 0
MOLECULAR TEMPLATES INC COM 608550109 9,220 1,374,047 SH   SOLE   1,374,047 0 0
NABRIVA THERAPEUTICS PLC SHS G63637113 507 425,650 SH   SOLE   425,650 0 0
PASSAGE BIO INC COM 702712100 49,892 5,009,219 SH   SOLE   5,009,219 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 187,060 5,827,415 SH   SOLE   5,827,415 0 0
REGENXBIO INC COM 75901B107 9,885 235,809 SH   SOLE   235,809 0 0
REPLIMUNE GROUP INC COM 76029N106 14,583 491,998 SH   SOLE   491,998 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 5,151 156,000 SH   SOLE   156,000 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 17,638 804,667 SH   SOLE   804,667 0 0
SUTRO BIOPHARMA INC COM 869367102 27,743 1,468,663 SH   SOLE   1,468,663 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 22,705 1,188,135 SH   SOLE   1,188,135 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103 30,540 1,417,157 SH   SOLE   1,417,157 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 54,984 3,123,107 SH   SOLE   3,123,107 0 0
TYRA BIOSCIENCES INC COM 90240B106 21,988 1,250,000 SH   SOLE   1,250,000 0 0
VAXCYTE INC COM 92243G108 58,593 2,309,554 SH   SOLE   2,309,554 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 24,761 1,505,200 SH   SOLE   1,505,200 0 0