Consolidated Statements of Operations (USD $)	12 Months Ended
	Dec. 31, 2014	Dec. 31, 2013
Income Statement [Abstract]
Licensing revenues	$ 57,321	$ 27,600
Operating expenses:
Research and development	4,962,196	12,991,502
Selling, general and administrative	7,415,049	6,680,983
Total operating expenses	12,377,245	19,672,485
Loss from operations	(12,319,924)	(19,644,885)
Other income (expense):
Interest income	978	3,052
Interest expense	(3,551,482)	(3,903,116)
Other income	1,888	11,566
Loss on disposals of assets	(1,114)
Gain on revaluation of derivative warrant liability	911,000	4,465,986
Other income (expense), net	(2,638,730)	577,488
Net loss before taxes	(14,958,654)	(19,067,397)
State income taxes	4,000
Net loss	(14,962,654)	(19,067,397)
Deemed dividend on beneficial conversion feature convertible preferred stock	(350,000)	(371,140)
Net loss applicable to common shareholders	$ (15,312,654)	$ (19,438,537)
Net loss per common share, basic and diluted	$ (1.24)	$ (2.33)
Basic and diluted weighted average common shares outstanding	12,308,254	8,359,837