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Consolidated Statements of Cash Flows (Unaudited) (USD $)
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Cash Flows From Operating Activities:      
Net loss $ (19,067,397) $ (12,332,008) $ (10,029,591)
Depreciation and amortization 391,595 145,155 47,916
Share-based compensation, net 1,244,342 1,409,562 836,866
Fair value of common stock and warrants issued for services 96,375 153,464 448,940
(Gain) loss on revaluation of derivative warrant liability (4,465,986) (3,683,676) 1,762,938
Non-cash loss on extinguishment of debt       1,514
Non-cash interest expense       12,159
Non-cash loss on disposal of assets    21,272 5,688
Non-cash debt financing costs    455,000   
Cash received from lessor as a lease incentive    236,974   
Amortization of discount on note payable 2,879,166 120,834   
Amortization of non-cash deferred financing costs 968,004 423,126   
Accounts receivable    37,065 104,423
Prepaid expenses and other current assets 26,405 98,124 (79,003)
Deposits and other assets (1,500) 9,999 (576)
Accounts payable (1,282,899) 1,953,921 (240,336)
Deferred revenue from licensing arrangements (27,600) (5,119) (302,059)
Accrued expenses and other liabilities (170,341) 668,642 505,184
Net cash used in operating activities (19,409,836) (10,287,665) (6,925,937)
Cash Flows from Investing Activities:      
Purchase of furniture, equipment and leasehold improvements (249,007) (1,487,091) (323,301)
Decrease (increase) in restricted cash 104,975 (157,463) 5,510
Net cash used in investing activities (144,032) (1,644,554) (317,791)
Cash Flows From Financing Activities:      
Proceeds from Montaur note payable    3,000,000   
Repayment of Montaur note payable (3,000,000)      
Proceeds from issuances of Common Stock, preferred stock and warrants, net of costs 26,864,570 3,278,869 8,918,190
Principal payments for capital lease obligations (2,527) (2,288) (2,071)
Proceeds from bridge notes       1,000,000
Repayment of bridge notes       (75,000)
Proceeds from the exercise of warrants    212,018 4,919,346
Proceeds from exercise of stock options    195,259 136,790
Net cash provided by financing activities 23,862,043 6,683,858 14,897,255
Net increase (decrease) in cash and cash equivalents 4,308,175 (5,248,361) 7,653,527
Cash and cash equivalents, beginning of period 3,747,210 8,995,571 1,342,044
Cash and cash equivalents, end of period 8,055,385 3,747,210 8,995,571
Supplemental Disclosure of Cash Flow Information and Non Cash Financing Transactions:      
Cash paid for interest 275 515 1,768
Accretion of dividend on Series B Perpetual Redeemable Preferred Stock       157,733
Deemed dividend on beneficial conversion feature of convertible preferred stock 371,140    1,975,211
Issuance of common stock in settlement of short term note       35,500
Conversion of notes payable and accrued interest into Series D Convertible Preferred Stock       1,006,000
Conversion of convertible preferred stock into Common Stock at par value 20,150    50,000
Redemption of Series B Perpetual Redeemable Preferred Stock for Series C Preferred Stock in connection with October 27, 2011 warrant exercises       1,701,672
Reclassification of derivative warrant liability to additional paid-in capital    61,520 2,272,597
Fair value of warrants included in stock issuance costs       41,363
Common Stock subscription receivable       6,667
Fair value of Common Stock issued in connection with settlement agreement    (82,000) 290,000
Cancellation of restricted Common Stock       5,250
Deemed dividend on repricing of warrants       4,559,761
Fair value of Commitment Warrant issued in connection with debt financing    4,840,000   
Fair value of Draw Warrant issued for note payable recorded as discount    3,000,000   
Fair value Draw Warrant issued for note payable recorded as debt financing costs    $ 455,000